Type 1 Diabetes - MOPH Qatar Diabetes Newsletter - 28th Feb 2018

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The gut and type 1 diabetes linked: study

Researchers at the University of Queensland have now discovered genetics plays a role in the development of this 'unhealthy gut' among type 1 diabetes patients. "We showed that genetic susceptibility and change in immune system function led to alterations in the microbiota," lead investigator Emma Hamilton-Williams said. "This means that changes in the microbiota in type 1 diabetes occur before symptoms develop, and are not just a side-effect of the disease," she explained. The study, published in journal Microbiome, involved mouse models and a large human study of twins in the UK.
19th Feb 2018 - SBS

The gut and type 1 diabetes linked: study

19th Feb 2018 - Daily Mail

New Study Demonstrates that DexCom CGM Significantly Reduces Hypoglycaemia in People with Type 1 Diabetes on MDI

Usage of DexCom CGM reduced the incidence of hypoglycaemic events by 72% for high risk individuals with type 1 diabetes on multiple daily injections (MDI) of insulin. DexCom, Inc today released the findings of the HypoDE study, a multi-centre, randomised controlled trial (RCT) which was discussed on Friday 15th February at ATTD. The study found that the use of Dexcom continuous glucose monitoring (CGM) reduces the frequency and severity of hypoglycaemic events among high-risk individuals with type 1 diabetes treated with multiple daily injections (MDI) of insulin.
20th Feb 2018 - Yahoo Finance

Rare Tumor Could Help Produce Insulin For Type-1 Diabetics, Study Shows

The key to getting them to replicate destroyed beta-cells, says Dr. Stewart, may lie in the DNA of rare benign tumors called beta-cell insulinomas. “Those small insulinoma tumors in the pancreas have the genomic recipe, if you will,” Dr. Stewart said. “They now have the genomic wiring diagram or roadmap for knowing how to make beta-cells replicate.” By sequencing every gene in these tumors, Dr. Stewart found the ones that put the brakes on beta-cell regeneration. As it turns out, certain drugs can take the brakes off the genes in normal beta-cells so they can start to divide. “We found lots of candidates and we’re in the process now of screening drugs that take off these other brakes and we’re making progress there,” Dr. Stewart said.
20th Feb 2018 - CBS New York

Diabetes early in life found to increase risk of fatal heart disease by 60%

Developing type 2 diabetes early in life increases your risk of death linked to heart disease by 60%. The risk of an early death from any cause surges 30% for those diagnosed with type 2 diabetes at 49 but the risk of death linked to cardiovascular disease is 60%. Research on 744,000 sufferers over 15 years to 2011 found the average diagnosis age was 59 and there were 115,363 deaths during the period. The risk of an early death from any cause surged 30% for those diagnosed 10 years earlier and there was a 60% higher risk of death linked to cardiovascular disease.
23rd Feb 2018 - Mirror.co.uk

Belfast schoolgirl almost dies of diabetic condition

The family of a 15-year-old Co Antrim girl who could have died after being stricken by a dangerous diabetic condition are calling for more awareness over the threat posed by the disease. On February 16 the Belfast Royal Academy student was rushed to the Royal Victoria Hospital with diabetic ketoacidosis (DKA), a complication faced by diabetics that occurs when the body starts running out of insulin. The disorder causes harmful substances - ketones - to build up in the body, which can be life-threatening if not spotted and treated quickly. The condition can cause swelling on the brain, leading to brain damage.
26th Feb 2018 - Belfast Telegraph

"The hardest thing is waking up and part of your body has gone"

I was duty manager at a professional football club and something got in my shoe and caused an ulcer on my toe. I was advised to give up work, which I wouldn’t do – bit of male pride, I suppose. The ulcer got worse and worse and worse, and in the end I had to have an amputation of one of the toes and the metatarsal hub. I have also got a muscle wasting disease in my legs [not related to the diabetes], which they diagnosed when I was in hospital, [and] they tried to pin and straighten my legs. Six months after the procedure I had a huge infection in the pins in my leg and I had to have intravenous antibiotics for a year. If my legs start getting ulcers again, because of all the other complications it could be a case of taking them off.
27th Feb 2018 - The Guardian