"Seqirus Media Monitoring" 9th Nov 2017

Seqirus mentions
Nearly 100 jobs to be created in Liverpool
Nearly a hundred new high tech jobs are to be created at the Liverpool manufacturing site of Seqirus as a result of major new investment announced today. Gordon Naylor, President of Seqirus, said: Our Liverpool site, the largest influenza vaccine manufacturing facility in the UK, and one of the largest in Europe, is well-placed to supply the UK with an enhanced influenza vaccine for people aged 65 years plus. It will also be an export success story, primed to supply this vaccine to countries where it is already licensed in Europe and North America, and to countries in Latin America and Australasia where regulatory submissions are ongoing”
Seqirus's Gordon Naylor is interviewed about the company's multi-million pound investment in jobs at its local flu vaccine manufacturing facility on the BBC Radio Merseyside Tony Snell in the Morning Show
Peter Salt, standing in for Tony Snell in the Morning interviews Seqirus's Gordon Naylor (7m 50 sec- 8m 25sec into the show) and he asks Gordon Naylor about the £40m investment in the local flu vaccine manufacturing site which will create just under 100 jobs for the city.
100 new high tech jobs created at the Liverpool manufacturing site of Seqirus (news feature begins 6m 50sec into programme and runs to 9m 15sec)
BBC North West Tonight reports on Seqirus' multi-million pound new fill-and-finish facility. With the visit of the UK Minister Greg Clark MP to open the factory the programme looks at how this facility will support the growing demand for Seqirus’ adjuvanted influenza vaccine designed for people aged 65+, (among other matters), and how this investment strengthens the reliability of flu vaccine
Will This Year's Flu Shot Be as Weak as Last Season's?
Lots of people came down with influenza last year despite getting a flu shot -- and researchers can't promise this season's vaccine will be any more effective. Last year's shot was only 20 percent to 30 percent effective because it was grown in eggs, according to the authors of a new report. Two new methods of producing vaccines are being tried: both these methods -- cell culture (Flucelvax) and DNA (Flublok) -- are licensed by the U.S. FDA
Your Good Health: Any approved vaccine can protect you from flu
Adults over 65 may benefit more from the high-dose trivalent vaccine (Fluzone High-Dose) or from Fluad, which contains an adjuvant. Adults age 18-64 with fear of needles might consider the intradermal low-dose quadrivalent vaccine (Fluzone intradermal). This uses a tiny (1.5-mm), ultra-thin needle. Another option for people with needle phobia is the standard trivalent vaccine (Afluria) using a jet injector device
Pandemic Influenza News
No new cases of bird flu in Western Cape over past week
The spread of the bird flu virus that has decimated parts the Western Cape's poultry industry may be be slowing down, according to Alan Winde, the Western Cape MEC for Economic Opportunities, a post that includes agriculture. In a statement on Wednesday Winde said that no new cases of bird flu have been reported in the province in the past week
Nearly 90000 birds culled because of 4 outbreaks of bird flu
In Bulgaria, nearly 90,000 birds have been killed so far because of outbreaks of avian influenza, said the press office of the Bulgarian Food Safety Agency. The first outbreak occured in the middle of October in the village of Stefanovo in the region of Dobrich. About 11,000 birds were culled.
One year after the first piece of avian flu evidence: Avian flu danger in Germany not banished
One year after the first detection of the highly dangerous pathogen H5N8 in dead waterfowl at Lake Plön in Schleswig-Holstein, infected wild birds are still being found in Europe and infected poultry flocks - an indication that the pathogen still occurs in the environment.
Preparing for winter for the best chance to prevent bird flu
In the UK the risk of avian flu returning, after last winter’s unprecedented number of outbreaks, is very real. The government has raised the official risk from low to medium, mainly in light of H5N8 outbreaks across Europe. Italy has reported 17 recent outbreaks of the virus, with one farm housing 850,000 layers – one of the country’s largest. In Germany, wild birds are once again turning up with the virus present, and Bulgaria has had two outbreaks
Germany: FLI Risk Assessment On Return Of HPAI H5 Avian Flu
Germany's FLI (Friedrich-Loeffler-Institut) has published a new risk assessment on the potential return of HPAI H5 this winter to Europe. When H5N8 returned to Europe in the fall of 2016 after an 18-month absence it brought with it new virulence, an expanded host range, and significant genetic changes. Today's risk assessment, while focusing on H5N8, also makes note of (as recently have both the UK's DEFRA and the ECDC) of H5N6, which is feared could eventually wing its way from Asia into Europe as have H5N8 and H5N1
Avian influenza outbreak: Chink in flu control
A major flaw has been exposed in Australia’s pandemic influenza management plan in the wake of the worst avian influenza outbreak to hit Europe. In 2014, Victoria’s health management plan for pandemic influenza recommended anyone handling pigs and poultry be routinely vaccinated with seasonal influenza vaccine. But poultry producers and industry staff contacted by The Weekly Times say they have never heard of such a recommendation and there was no mention of the need for vaccination on the Department of Health’s or Agriculture Victoria’s websites
PHL on track to regaining bird flu-free status by year-end
The Philippines may regain its bird flu-free status before the end of the year, as the government would soon be able to complete the roll out of all the necessary measures to manage the avian-influenza virus. The Bureau of Animal Industry is planning to notify the World Organisation for Animal Health that the Philippines is already bird flu-free by December 20, more than four months after the virus was discovered in some towns in Central Luzon
$1 million cooperative agreement will help ISU veterinarians strengthen avian influenza response
An Iowa State University center has received a $1 million federal cooperative agreement to enhance preparedness for future outbreaks of highly pathogenic avian influenza, such as the 2015 crisis that forced U.S. egg and poultry producers to eliminate millions of birds
Industry News
GlaxoSmithKline appoints Hal Barron as R&D chief
Emma Walmsley has taken the next step in reshaping GlaxoSmithKline’s R&D operation by appointing Hal Barron, a renowned US expert in drug development, as chief scientist to succeed Patrick Vallance. Dr Barron is the latest major appointment the chief executive has made as she looks to stamp her authority on the pharmaceuticals division and improve GSK’s lacklustre performance in finding new blockbuster drugs
Novavax in position to seek flu vaccine approval in 2019
Novavax could file for regulatory approval to commercialize its flu vaccine candidate as early as 2019. CEO Stanley Erck said the company fully enrolled its phase 1/2 clinical trial for its flu vaccine candidate and expects data back by the end of the year. "Assuming that a variety of stars line up, this could lead to a phase 3 pivotal trial this time next year," Erck said. That could mean the company would file a biologics license application by 2019
Collaboration between GPs and pharmacists key to increased flu vaccine uptake
Primary care workers, including pharmacists and GPs, should collaborate rather than compete to boost influenza vaccine uptake, according to David Bearman, chair of Devon Local Pharmaceutical Committee. Bearman was speaking following the completion of a Pfizer-sponsored six-month pilot collaboration between the Beacon Medical Group, which covers 33,000 patients across five GP surgeries and local branches of Boots, Well Pharmacy and Day Lewis. The programme aimed to increase flu vaccination uptake by building reciprocal links between GPs and pharmacists
New needle-free vaccines could mean the end of the flu shot
An article in Chemical & Engineering News (C&EN) describes advances in injection-free vaccination methods that are showing promise. Now that FluMist is losing its appeal, other solutions are being researched: oral administration, a spring-powered injector to shoot a vaccine in a fluid stream through the skin and into the muscle, a much smaller needle, and finally a small patch covered with microneedles
Flu season is here, and experts are already concerned
Last year's seasonal flu vaccine effectiveness was just 42%, the US CDC estimated. Even if vaccinated, people had inadequate protection against the flu. This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a study. This vaccine mutation resulted from an egg-based manufacturing process commonly used today
Why the flu vaccination is so important to me
Olympian runner Paula Radcliffe explains why, being asthmatic, she takes flu vaccination seriously, and has teamed up with Sanofi Pasteur to encourage people to get their flu shot
Academic studies
Flu more likely to send people in poverty to hospital, Vanderbilt study says
A person’s age, ethnicity, and even location can predict whether a case of the flu will become severe enough to send the patient to the hospital, according to research from the Vanderbilt University in Nashville. The study found that patients living in poverty or crowded living quarters, or where a female served as head of household, were more likely of being put in the hospital over a case of influenza
Be happy and that may be the best way to avoid catching the flu
Smile this winter you will avoid catching the flu. This is the message coming from a study conducted by the University of Nottingham and published in Brain, Behavior and Immunity. According to researchers being in a good mood on just the day you get the influenza vaccine makes an immediate beneficial effect on the immune system, as it produces more antibodies than a less happy person would
Egg-Based Flu Vaccines Dealt Another Blow as Researchers Move Closer to Universal Vaccine
Following recent findings on why egg-based flu vaccines aren’t working well to prevent illness, a new study detailed another reason why the egg-grown vaccine is not protecting against the H3N2 strain of influenza. In 2014 researchers discovered that hemagglutinin gene clade 3C.2a influenza A (H3N2) strain developed a mutation on its outer layer protein, preventing human antibodies from attaching to and destroying the virus. Although the vaccine for the 2016-2017 flu season was updated to include a different protein, the researchers found that the vaccine developed a new mutation while growing in eggs, producing antibodies that were also weak against H3N2
Researchers discover new mechanism for battling influenza
Researchers from the University of Colorado Boulder and University of Texas at Austin have uncovered a previously unknown mechanism by which the human immune system tries to battle the influenza A virus. The paper focuses on two key molecular players: a human protein called TRIM25, which was recently discovered to play an important role in the human immune response to flu infection; and a protein called NS1 present in all strains of the influenza A virus and shown to bind TRIM25 to keep it from doing its job
Flu Season, and the Links Between Mental Health and Infectious Diseases: Public Health Watch
Researchers in China have found a link between the seasonal flu virus and mental health, and the findings should be a reminder (or perhaps a wake-up call) for clinicians treating patients with flu specifically and infectious diseases in general. In a study published in October 2017 in BMC Infectious Diseases, researchers in China found that at least 60% to 75% of patients with influenza also experience anxiety and/or depression
Pediatric influenza news
WHO recommends that pregnant women get vaccinated against the flu
The World Health Organization recommends annual flu vaccination in pregnant women at any stage of pregnancy. Despite the widespread introduction of influenza vaccine for pregnant women in the region, regional vaccination coverage is approximately 59%, with a total of 32 of the 52 countries offering constructive flu vaccination campaign protection for pregnant women
Parents urged to take up free flu vaccine
Parents across Buckinghamshire are being encouraged to take up the offer of a free flu vaccine for their children. The child-friendly nasal spray is quick, effective and painless squirt into each nostril
Influenza Vaccines in Pediatric ERs Likely Cost-Effective
Influenza vaccination in the pediatric emergency department setting appears to be a cost-effective strategy, according to a study. Rebecca J. Hart, M.D., from the University of Louisville in Kentucky, and colleagues compared the cost-effectiveness of four strategies for PED-based influenza vaccine
Over 65’s influenza news
Should Grandparents Get Flu Shots? Experts Explain
A startling 90 percent of deaths from the flu occur among the elderly, according to Healthline. While every adult should receive a flu shot, it's especially important for pregnant women, the elderly, and anyone interacting on a daily basis with a newborn baby. "It is important to remember that babies aren’t vaccinated themselves against flu until they reach 6 months of age," explains Amesh Adalja, MD, who studies pandemics and infectious diseases at the Johns Hopkins Center for Health Security
General Influenza News
This year's influenza vaccination campaign for USL staff in Bologna is under way
The USL healthcare company in Bologna, launched a flu vaccination campaign aimed at doctors and nurses, which sought to protect them against influenza, and, above all, protect the health of their patients.
The new flu vaccination in Trieste is aimed at giving vaccine protection for the higher risk over 65 group
With stronger double-dose vaccines and more care in trying to reach the groups most affected, local healthcare experts in Trieste are aiming to give flu vaccine protection for as many of the higher risk over 65 group as possible to meet the Italian government target of 75%
Brest: getting your flu shot
In France, people are being reminded to get their flu shot, especially if they belong to an 'at-risk' group. Nurses offices are working longer hours to ensure more people take up the vaccine
GPs miss out on funding as data reveal pharmacies delivered 1m flu jabs last year
In the UK, community pharmacies delivered 60% more flu vaccinations in 2016/17 compared with the year before, and received payments worth over £8.6m for delivering the service across the season, official data show
Leading Organizations Partner to Raise Awareness About the Healthcare Professional's Important Role in Influenza Prevention
With flu season officially here, three leading health organizations, the National Association of Pediatric Nurse Practitioners, HealthyWomen and Families Fighting Flu, urge healthcare professionals to understand the influential role they have in flu prevention by proactively recommending an annual flu vaccination to patients. Through this collaboration, Do You Know the Flu?, the organizations aim to arm and educate healthcare professionals to better understand how they have a profound and real impact on a person's decision to receive an annual flu vaccination.
Government launches winter campaign, encourages flu vaccine
In Ireland, the Government has launched its 'Be Winter Ready' campaign, with the focus of this year's campaign on health preparedness for older people, including promoting flu vaccinations. Minister for Health Simon Harris appealed for people to get the flu vaccine as soon as possible
Children’s flu vaccine figures among highest in South West
More than 70 per cent of children aged five to six years old in North Somerset received the flu vaccine last year, compared to a South West average of 59 per cent. Flu vaccine uptake among children aged six to seven is 68 per cent – 55 per cent in the South West – while the figure among children aged seven to eight stands at 65.5 per cent, more than 13 per cent higher than the South West average
Study finds 40 percent of doctors work while sick. Here"s how Philly hospitals handle sick days
Four in 10 health-care professionals report to work while experiencing influenza-like symptoms, working a median of three days, according to the U.S. Centers for Disease Control and Prevention. The findings were based on a survey of nearly 2,000 health-care workers.
Adult Mumbaikars believe vaccines are only for kids: Study
A third of adult Mumbaikars believe vaccines are meant only for children, found a survey. The concept that vaccines can protect adults, especially senior citizens, from virulent attacks of flu or pneumonia is clearly not known
MOHAP launches seasonal influenza awareness campaign
The Ministry of Health and Prevention, has launched an awareness campaign on seasonal flu which will run until 8th December 2017. The campaign targets healthcare professionals in the ministry and the private sector in the Northern Emirates. It includes lectures and training on updated clinical information of the influenza virus, highlighting its risks, and ensuring the importance and effectiveness of the available vaccine
Flu jab 2017: The trick to making your vaccine more effective
Feeling positive on the day of your flu jab could make it 14 per cent more effective, it’s been revealed. The findings could help to better protect those with a weakened immune system, including the elderly. Last year, the flu jab had zero effectiveness on over-65s, it was claimed. Following the research, supermarket Asda has unveiled plans to start a ‘joke-telling’ initiative, in a bid to boost the vaccine’s potency
Flu jab side effects, if it’s safe for children and how to get a free NHS jab at Boots, Asda and Tesco
A roundup of flu vaccination related information, including side effects, who the flu vaccine is free for in the UK, whether it is safe for children and when we can expect a universal flu vaccine
'Case of when, not if' - Kiwis warned another deadly pandemic will strike
It's been almost a century since New Zealand suffered its deadliest virus outbreak ever, with one leading researcher saying it's only a matter of time before the next pandemic hits. Dr Nikki Turner from the Immunisation Advisory Centre said: "The flu season this year in New Zealand was relatively mild, in contrast to Australia who had one of the worst flu seasons ever." Her best advice to make sure the risk of a pandemic is minimised is for healthy New Zealanders to get the flu vaccine
Number of people with flu going to rise soon, Minister warns
In Ireland, the numbers of people reporting with the flu are “going to rise over the coming weeks”, putting the lives of elderly and vulnerable people at risk, Minister for Health Simon Harris warned. Mr Harris urged all frontline medical staff to get the flu vaccine immediately and particularly mentioned nurses working with susceptible people outside of hospital settings, in situations such as nursing homes
Burden of disease
Health officials confirm first two flu cases in Pueblo County
Public Health officials in Pueblo have announced the first two confirmed influenza “flu” cases in Pueblo County. Both individuals are senior citizens, according to officials. “This first hospitalized flu cases confirms flu is circulating in the Pueblo community,” said Jody Carrillo, division director at the Pueblo City-County Health Department. “Now is a good time to get the flu vaccine as the vaccine takes about two weeks for protection to set in,” Carrillo added