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"Seqirus Media Monitoring" 13th Nov 2017

Seqirus mentions
Nearly 100 jobs to be created in Liverpool
Nearly a hundred new high tech jobs are to be created at the Liverpool manufacturing site of Seqirus as a result of major new investment. Gordon Naylor, President of Seqirus, said: "Our Liverpool site, the largest influenza vaccine manufacturing facility in the UK, and one of the largest in Europe, is well-placed to supply the UK with an enhanced influenza vaccine for people aged 65 years plus. It will also be an export success story, primed to supply this vaccine to countries where it is already licensed in Europe and North America, and to countries in Latin America and Australasia where regulatory submissions are ongoing"
Liverpool flu firm creates 100 hi-tech jobs
Liverpool is to benefit to the tune of 100 new high-tech jobs and it’s all connected to combatting flu. The BBC reports the new roles are being created due to flu vaccination firm Seqirus’ £40m project, which will allow new vaccines to be created more quickly at its plant in Speke. The plant provides around half of the flu vaccine used in the UK
Emails show Battle Creek VA worries about some flu shots
An email written on October 16 and obtained by the Newschannel 3 I-Team shows internal worries over a flu vaccine administered by the Battle Creek VA due to particulates being found in the serum. The manufacturer of the vaccine, Seqirus, according to the email, was contacted immediately to inspect the batch of vaccines affected. The company later determined the vaccines that may have been administered with the particulates were safe
Docs push flu shots for adults 65 and older
With some indications that this year’s flu season could hit older adults particularly hard, doctors are encouraging people to not only get their flu vaccinations, but pay careful attention to which vaccination they get. There are two shots available in the U.S. specifically for people over 65: Fluzone contains four times the amount of antigen contained in traditional flu shots; Fluad contains an adjuvant that enhances immune response
Pandemic Influenza News
Avian influenza detected on Jeju Island
The South Korean government said an avian influenza virus has been detected in wild bird droppings on the southern island of Jeju. The Ministry of Agriculture, Food and Rural Affairs said an H5N2 strain of the bird flu virus was detected in excretions of wild birds in the northeastern part of the island Nov. 6. The ministry will check to see if the virus is highly pathogenic, with a result expected in a couple of days
Update from Tivoli on the recent outbreak of H5N8 avian flu in the region
On 3rd November there was an H5N8 outbreak of avian flu in the Tivoli region. In close coordination with local health commissioners the mayor has signed an order to seize the non-commercial livestock where the infection was detected
Bird flu: The worst may be over in WC
Officials say there have been no new reported bird flu cases in the province of Cape Town in South Africa, signalling the worst may be over
First Consultations Held On WHO Pandemic Flu Framework Options
The World Health Organization is consulting member states and stakeholders on the future of its mechanism to help prepare the world for the next influenza pandemic. It is particularly asking whether countries should submit not only the biological samples of their influenza viruses, but also their genetic information through the mechanism. Also in question is whether the mechanism should be extended to cover seasonal influenza
What You Need to Know About Bird Flu
Some strains of bird flu (namely the H7N9 variety) appear to have become increasingly virulent to humans—the outbreak earlier this year in China is one example. But the Centers for Disease Control says that overall, human cases are still rare and sporadic.
WUR: bird flu virus H5N8 came from migratory birds from Russia
Russian migratory birds brought bird flu viruses to the Netherlands last November. The viruses were different from those that caused an outbreak of avian influenza in 2014. Scientists believe that the H5N8 virus can very quickly change genetic composition, increasing the risk of infection in humans and animals. This is stated in a research conducted by the Bioveterinary Institute of Wageningen University and Research Center (WUR) for the recent bird flu outbreak .
Dead swan in Shimane found to be infected with avian flu
The Environment Ministry said a dead wild swan found at a western Japan lake was infected with a highly pathogenic avian influenza virus, confirming it as the first bird flu case in the country this season. A detailed examination conducted at Tottori University determined the presence of the H5N6 influenza strain, which has caused severe outbreaks in Japan and Asia in the past, according to the ministry
Why Did the 1918 Flu Kill So Many Otherwise Healthy Young Adults?
Experts fear that a new pandemic, of influenza or another infectious agent, could kill millions. Bill Gates is leading the funding effort to prevent this. An influenza virus is currently killing chickens in Asia, and has recently killed humans who had contact with chickens. This virus is of a subtype that has not been known to cause pandemics. It has not yet demonstrated the ability to be transmitted from person to person. However, whether this ability will arise during ongoing virus evolution cannot be predicted
Russian migratory birds brought the avian flu last year
The bird flu viruses that were discovered in the Netherlands a year ago were brought into the country from Russia by migratory birds. This is the findings of a study by the Bioveterinary Institute of Wageningen University and Research Center (WUR). Fifteen poultry farms were cleared and more than 727,000 animals were killed and numerous wild water birds were euthanized too
Industry News
Two-thirds of adults are not up-to-date on their vaccines, survey finds
Despite the World Health Organization citing immunization as one of the most powerful and cost-effective interventions in public health, a new survey conducted by Ipsos MORI and sponsored by GSK Vaccines in Brazil, Germany, India, Italy and the United States found that 68% of adults are not up-to-date with the vaccines recommended for them. Almost three in 10 adults report not having had any of the vaccines potentially relevant to them within the past five years
What’s the Link Between Flu and MS Relapses?
In the U.S., the CDC is urging everyone age 6 months or older to get the flu vaccine. Doctors say the need for a flu shot is especially important for people with multiple sclerosis. Dr. Amesh Adalja, an infectious disease specialist, recommends that MS patients get a flu shot that covers four different strains of the flu. And a particular type of quadrivalent vaccine may be the most effective, he says. “There’s emerging data that the recombinant quadrivalent vaccine called Flublok has more protection”
British Biotech Develops Vaccines that Ignite our Entire Immune System Against Disease
Vaccitech is taking current shortcomings to make a better vaccine. So far, Vaccitech looks to be succeeding. Its universal flu vaccine generates a strong T-cell response and a better antibody response than the standard flu virus alone. Vaccitech will come up against fellow Brits, VirionHealth, which achieved a £13M IPO to support the development of its universal vaccine
Academic studies
How flu changes within the human body may hint at future
Researchers tracked viral evolution in four cancer patients who had flu infections lasting several months. How did flu change within these long infections? By sequencing viruses from different times during the infection and comparing their genomes, they were able to identify new mutations and track their fates
Flu Vaccine Could Provide Long-Lasting Protection
A new flu vaccine currently being tested in animals could provide long-lasting protection against various strains of influenza. David Putnam, PhD, Associate Professor in the Nancy E. and Peter C. Meinig School of Biomedical Engineering at Cornell University, helped create the vaccine. He told Drug Topics that researchers are hopeful the vaccine could be effective in humans for up to 5 to 10 years
Timescales of influenza A/H3N2 antibody dynamics
Because individuals are infected with multiple flu strains during their lifetime and each virus can generate a cross-reactive antibody response, it is challenging to quantify the processes that shape observed immune responses, or to reliably detect recent infection from serological samples. Using a Bayesian model of antibody dynamics at multiple timescales, researchers explained complex cross-reactive antibody landscapes by inferring participants' histories of infection with serological data from cross-sectional and longitudinal studies of influenza A/H3N2 in southern China and Vietnam
Pediatric influenza news
Youngsters to receive free flu vaccinations as part of country-wide push to keep kids healthy
Public Health England has urged parents from Burton, Uttoxeter and South Derbyshire to make sure their children are vaccinated against flu ahead of the winter period. For the first time this year, school children in year 4, can receive the free flu vaccination. Youngsters aged at least four, in reception classes, along with youngsters in school years one, two and three can receive a free flu vaccination
CDC Study Shows Up to 7.7-fold Greater Odds of Miscarriage After Influenza Vaccine
Robert F. Kennedy, Jr., chairman of the World Mercury Project (WMP), writes about the recent study linking spontaneous abortions in women to flu vaccines. He writes: "Thimerosal exposure has previously also been associated with birth defects, tics, speech and language delays (in more than one study), among many other developmental disorders. My book, Thimerosal: Let the Science Speak, details over 400 studies on the toxic effects of thimerosal. Given all of this evidence, it is now past time to completely protect our children and pregnant mothers from this potent neurotoxin"
Doctors stress the importance of using vaccines during the Pediatric Infectious Disease Congress
A the inauguration of the XVII Latin American Congress of Pediatric Infectious Diseases and the XXX Inter-American Congress of Pediatric Infectious Diseases, the president of the Mexican Association of Pediatric Infectious Diseases (AMIP), Antonio Luévanos Velázquez, said that both events are recognized by the medical community as high-level spaces where academic level expertise thrives and permits an exchange of knowledge with recognized experts and opinion leaders from all over the world
Pregnant women need to protect against swine flu
In India, pregnant women should be made aware of the precautionary measures that they can take to prevent contracting swine flu, such as staying away from people suffering from influenza and avoiding crowded places. Of the 300 people who tested positive for swine flu this year, 35 have been pregnant women who required serious medical management for mother and the child to be saved. Five pregnant women have died of swine flu in Telangana in this year
Over 65’s influenza news

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General Influenza News
H3N2 influenza virus isolated in university lab in Palermo
The H3N2 influenza virus was isolated in a Palermo lab. "Isolation of the H3N2 occurred in our lab a couple of weeks ago. It was found in a traveller returning from a North European country," explained Francesco Vitale, professor of Hygiene and Preventive Medicine at the University of Palermo. Authorities are now stepping up the flu vaccination programme in response
Flu vaccination campaign begins on November 18
Preparations are ongoing by the National Center for Disease Control to carry out the seasonal flu vaccination campaign starting from November 18 throughout Libya. The 12-day campaign will target pregnant women, elderly persons aged 50 years and above, health service providers working in the health centers and those suffering from chronic diseases such as diabetes, heart disease, respiratory diseases, kidneys, nervous system and the HIV
Flu: five reasons to get vaccinated
In the Vosges area of France, readers are being encouraged to get their flu shot because of five main reasons: it's free, harmless, protects others, helps avoid complications from the virus and people should not believe anti-vaxxers (and Tamiflu is not a very efficient way to combat the flu)
Why it's your job to get a flu shot
Almost everyone should get a flu shot, preferably before the end of October, though flu vaccine should still be administered until the season is over, usually by late spring. The influenza vaccine has been shown to be one of the most important preventive measures against the flu.
The ISSSTE will hand out two million flu vaccine doses
With the launch of a call to increase the level of care for children under five, elderly people, pregnant women and the chronically sick, whose immune systems are much weaker, the general director of ISSSTE, José Reyes Baeza Terrazas, launched a vaccination campaign against the flu virus, for which there are two million vaccination doses on hand, which are to be spread to this at-risk population in general, whether or not they are beneficiaries of any given health institute
Is San Diego headed for a big flu season?
Australia, which often serves as a sneak peek of America’s flu season, is coming off a significant bout of influenza-related illness just as cases are starting to spike in San Diego. Dr. Wilma Wooten, the county’s public health officer, says it's too early to tell for sure whether it will be as bad in the U.S. “We don’t have enough information yet to tell how severe the flu season is going to be,” Wooten said
Theresa May tells NHS boss he will be accountable for winter performance
Theresa May has made NHS boss Simon Stevens personally responsible for ensuring the health service does not end up in a crisis this winter. Bosses of NHS trusts and doctors groups are acutely anxious that bed shortages, nurse and doctor shortages and their inability to discharge patients because of inadequate social care could cause a “winter of woe”, especially if a major flu outbreak does occur. The NHS is putting £237m into the biggest ever flu vaccination campaign in an attempt to limit the numbers being affected by it in coming months
Universal Flu Vaccine Could Prevent Widespread Epidemic, Researchers Say
“Despite countless breakthroughs in medicine since the 1918 flu pandemic, one key advance continues to elude researchers. Without a universal vaccine to combat ever-changing flu strains, another pandemic threatens to overwhelm U.S. health care system", warns Tom Inglesby, MD, of the Johns Hopkins Bloomberg School of Public Health
New needle-free vaccines could mean the end of the flu shot
Taking the needle out of immunizations could help boost vaccination numbers, particularly in places where resources are limited. Toward this end, researchers continue to seek alternative vaccine-delivery systems. Oral administration is one possibility. Another option was approved by the U.S. FDA in 2014 for most adults. It uses a spring-powered injector to shoot a vaccine in a fluid stream through the skin and into the muscle
The flu shot: Who should get it and why
The National Advisory Committee for Immunization in Canada, which makes all vaccine recommendations in Canada, advises that everyone six months of age and older is immunized against influenza every year. In some provinces and territories, the government pays for everyone to have the vaccine. In some regions, only high-risk people (such as young children, older adults and people with chronic medical problems or in nursing homes) are paid for and others have to pay themselves
Hospital chief praises workers for flu vaccine project
Frontline NHS health staff in South Tyneside and Sunderland have been praised for leading the fight against flu by having a vaccination. Since South Tyneside and City Hospitals Sunderland NHS Foundation Trusts launched their annual staff vaccination programmes last month, well over half of the workforce of more than 10,000 have been vaccinated - including chief executive Ken Bremner and other members of the Trusts’ joint executive management team
Influenza cases on the rise
More Central Albertans are rolling up their sleeves to be immunized against the flu this season. As of Nov. 4 a total of 61,499 people received the vaccination, up from 43,290 the previous week, at Alberta Health Services Central Zone clinics, doctors offices and pharmacies. Across the province 639,305 Albertans have been immunized
A dose of research on the flu shot
Despite the well-publicized recommendations to get a flu shot every year in the U.S., many do not get the vaccine. Researchers at the National Center for Immunization and Respiratory Diseases found that while nearly all adults surveyed were aware of the flu vaccine, only half reported vaccination
Pyrénées-Orientales: flu vaccine fails to attract patients
In the Pyrénées-Orientales area of France, the flu vaccination uptake is disappointing and has prompted local health authorities to redouble their efforts to reach at risk groups as less and less people get vaccinated year on year
Burden of disease
SKIMS hushing up swine flu deaths, says DAK
Doctors Association Kashmir (DAK) on Saturday said authorities at SK Institute of Med­ical Sciences (SKIMS) are hushing up swine flu deaths and cases. “That puts the whole population at risk of a deadly outbreak,” said President DAK and flu expert Dr Nisar ul Hassan. “While it is mandatory to re­port and inform public about these deaths and cases, health officials are concealing them,” he said
India sees more than 20-fold jump in swine flu cases in 2017
In India, according to a latest report on seasonal influenza (H1N1) released by the ministry of health and family welfare’s Integrated Disease Surveillance Programme (IDPS), 8,543 people succumbed to deadly swine flu virus between 2010 and October 2017. More importantly, the number of cases across the country this year has seen a more than 20-fold rise from last year
Greece reports first victim of flu this autumn
A 79-year-old man was the first recorded victim of influenza in Greece this autumn, Greek national news agency AMNA reported. The patient who belonged in a population segment at high risk of flu complications, was not vaccinated and died from complications after contracting flu type A (H3N2), according to the Greek Center for Disease Control & Prevention (KEELPNO)
Alberta records 4 flu deaths in 2017-18 season as Calgary cases rise
There have been four flu-related deaths in the province of Alberta, Canada, so far in the 2017-18 season, according to the latest report from Alberta Health Services. An update posted Thursday reported a total of 202 lab-confirmed cases of influenza A and 42 cases of influenza B in Calgary for the period between Aug. 28 and Nov. 4
Teenager dies with suspected H1N1 in Itapetininga
A 14-year-old girl died on suspicion of H1N1 flu on Friday (10), in Itapetininga. In a statement, the city said that it had sent material for examination and was seeking confirmation of the disease to the Instituto Adolfo Lutz in Sorocaba, and the results should be available in 20 days.
Swine flu outbreak in Maharashtra, 71 deaths in one month
Over the course of this year, 6250 cases of swine flu have been detected in the sate of Maharashtra in India. In fact, data from the Maharashtra State Health Department shows 71 swine flu deaths reported in one month across the state and the situation seems to be worsening
Arizona flu cases continue upward climb, health officials say
The number of local influenza cases in Arizona spiked upward last week, but the numbers are not considered unusual, health officials said. Across the state, 250 influenza cases have been reported so far this flu season, which began Oct. 1, the Arizona Department of Health Services said
1 flu death reported in North Carolina; 3 total for the season
State health officials say a third person has died from the flu in North Carolina. The state Department of Health and Human Services said that like the two victims reported last week, the latest flu death involved a person 65 years of age or older
US flu picks up; More H5N8 avian flu in Italy
The CDC, in its weekly FluView report, noted that flu cases are rising across the U.S., and Louisiana and South Carolina are seeing moderate activity. Overall, flu activity is still low, with only 13 states reporting influenza cases. Across the country, the proportion of people seeing medical providers for influenza-like illnesses was 1.8%, below the national baseline of 2.2%. H3N2 is still the dominant circulating strain
Diabetic woman is the first recorded case for Influenza B
In Mexico, a diabetic women who suffers from other chronic diseases is the first recorded case of Influenza B this year. She is being treated but people are being reminded to get their flu shot, especially if they belong to an at-risk group