"Seqirus Media Monitoring" 21st Nov 2017

Seqirus mentions
'Use adjuvanted flu vaccine in over-65s next winter', JCVI recommends
GPs should consider using an adjuvanted flu vaccine for the 2018/19 flu season as they are more effective than currently available vaccines, the Joint Committee for Vaccinations and Immunisations (JCVI) has recommended. The JCVI acknowledged in its November meeting that the adjuvanted vaccine Fluad is both more cost effective and more clinically effective than the currently available flu vaccine for over-65s
Why now is a good time for a flu shot
There are two flu vaccines intended for people who are sixty-five years and older. The “high dose” vaccine has four times as much antigen as the regular flu shot and has been found to be 24% more effective in preventing flu infections. Another option is the “adjuvanted” flu vaccine, Fluad. This vaccine is designed to create a stronger immune response to vaccination, and one study showed that Fluad was 63% more effective than standard dose, unadjuvanted flu shot
Pandemic Influenza News
Gov't to penalize farms for bird flu outbreak
The Korean government plans to penalize chicken and other poultry farms infected with avian influenza if they are found to have been negligent in preventing the outbreak of the highly infectious virus, the top agriculture policymaker said Monday. This warning came a day after a highly pathogenic strain of H5N6 flu was discovered at a poultry farm with 12,000 ducks in Gochang
CHP notified of human case of avian influenza A(H5N6) in Guangxi
In Hong Kong, the Centre for Health Protection received notification of an additional human case of avian influenza A(H5N6) in Guangxi from the National Health and Family Planning Commission. The patient had contact with live poultry and exposure to live poultry markets before the onset of symptoms
H5N6 sickens Chinese man, strikes duck farm in South Korea
In new H5N6 avian flu developments, a Chinese man is hospitalized in critical condition after he likely contracted the virus from poultry, and South Korea reported an outbreak from the highly pathogenic virus at a commercial duck farm
Industry News
BiondVax and NIH Sign Clinical Trial Agreement for a Phase 2 Trial in the U.S. with BiondVax's Universal Flu Vaccine
In the U.S., BiondVax announced the signing of the clinical trial agreement for a Phase 2 clinical trial with NIAID. The study is titled "A Phase II, Double-Blind, Multicenter, Randomized, Placebo-Controlled Trial to Assess the Safety, Reactogenicity, and Immunogenicity of Two Doses of Multimeric-001 (M-001) Followed by Seasonal Trivalent Influenza Vaccine." It is designed to evaluate the cell mediated immunity directly induced by BiondVax's universal flu vaccine candidate M-001, as well as M-001's priming effect to enhance the immunogenicity of current seasonal influenza vaccines
Vaxigrip influenza vaccine shipped to Ukraine was made in France
The influenza vaccine Vaxigrip shipped to Ukraine for the current epidemiological season was made in France, Head of the vaccines department of Sanofi in Ukraine Olena Yentina has told Interfax-Ukraine. A parliamentary committee had sent a request to the Health Ministry asking for all the documents concerning supplies of flu vaccine shipped by Sanofi to Ukraine as they believed it was made in India
Academic studies
MIT researchers gain new insight on how flu spreads from cell to cell in the body
MIT researchers say that for the first time they have been able to see how the flu virus spreads from cell to cell in the body. Previous studies have shown that a protein called M2 was involved in the separation of the flu virus from its host cell; MIT researchers have now detected the incredibly small and dynamic flu protein
Antiviral Prescribing for Flu Examined Among High-Risk Patients
High-risk outpatients with acute respiratory illness may be infrequently prescribed influenza antiviral medications even though they may benefit most from treatment, according to findings published in the journal Clinical Infectious Diseases. To better understand the prescribing habits of antivirals for influenza treatment, researchers specifically looked at what factors impacted how these medications were utilized. Currently, clinicians can choose among amantadine, oseltamivir, rimantadine, or zanamivir to treat the infection
H1N1 infection may increase risk of type 1 diabetes
Infection with H1N1 influenza has been linked to the development of autoimmune disorders. Researchers from Norway used national registry data to explore if the virus could also be linked to the development of type 1 diabetes. Results showed that people with laboratory-confirmed H1N1 or those hospitalised with flu during the 2009 H1N1 pandemic were twice as likely to develop type 1 diabetes as the general population
Flu Researchers Discover New Mechanism for Battling Influenza
Researchers from the CU Boulder and University of Texas at Austin have uncovered a previously unknown mechanism by which the human immune system tries to battle the influenza A virus. The paper focuses on two key molecular players in the story of influenza infection: a human protein called TRIM25, which was recently discovered to play an important role in the human immune response to flu infection, and a protein called NS1, present in all strains of the influenza A virus and shown to bind TRIM25 to keep it from doing its job
"Alarming" rate of health care professionals work while having flu symptoms: study
More than 40 percent of health care professionals who reported at least one symptom of influenza during a recent flu season did not stay home from work, according to a new study from the CDC. Researchers looked at data from a survey of 1,914 health care workers conducted during the 2014-2015 flu season. They found that of the 414 respondents who reported at least one symptom of the flu, 183 chose to work regardless
State-Level Influenza "Nowcasting" Remains a Thorny Issue
A new study leveraging online search trends to gain a picture of current, local influenza outbreaks is showing some signs of promise, though researchers say they remain hamstrung by a lack of access to complete live data. Researchers from Columbia University recently developed their own “nowcasting” model, which used flu-like illness data at the state level, along with web-based search activity from Google Extended Trends. Their findings, published earlier this month, were mixed
Pediatric influenza news
New study finds the flu vaccine can prevent hospitalization in children
New Canadian research has found that children who have been vaccinated against influenza are significantly less likely to end up in hospital because of the virus. Overall, fully vaccinated children aged two- to four-years-old saw their risk of hospitalization due to influenza drop by 67 percent while those aged six to 23 months saw their risk drop by 48 percent
Flu vaccinations happening too late, says disgruntled parent
In Scotland, an Angus parent has criticised the flu vaccination programme at her child’s school after learning the jabs would not be delivered until a week before Christmas. NHS Tayside’s immunisation team has postponed its session at Lochside Primary School in Montrose to December 18
Over 65’s influenza news
Influenza vaccination important - especially for at-risk groups
The Standing Vaccination Commission (STIKO) at the Robert Koch Institute (RKI) strongly recommends flu vaccination especially for certain groups of people who are at particular risk for severe complications: pregnant women, over 60s, residents of nursing homes, carers and all medical staff
Assertive Approach Recommended for Flu Vaccination Discussions
William Schaffner, MD, medical director for the National Foundation for Infectious Diseases’ (NFID) and infectious disease physician at Vanderbilt, explains how health care providers can work towards getting patients who are aged 65 and older to receive a flu shot, using a very assertive approach
Another call for better aged care standards
In Australia, the daughter of a Latrobe aged care resident who almost died in an influenza outbreak, has added to calls for improvements in aged care standards. A review by the Australian Aged Care Quality Agency of how Strathdevon and an interstate aged care facility dealt with the influenza outbreak, which killed six Strathdevon residents, revealed errors in infection control
General Influenza News
Flu vaccines - the problem lies inside the egg
A recent article in PLOS Pathogens shows that egg production is a problem if companies want to make vaccines against the virus subtype H3N2. Since the spread of influenza caused by the H3N2 subtype, virologists who produce the seasonal influenza vaccine have attempted to include this virus. Despite these efforts, only 33 percent of newer influenza vaccines were effective against H3N2 viruses
Vaccination in pharmacies in demand
One pharmacy offering the vaccination service said it has been pleasantly surprised by the positive reaction to the service they offer the public. The Swiss Pharmacists Association slogan ' the flu does not wait for an appointment' seems to resonate with some and many have come to get vaccinated against the flu
Portalegre: Vaccination rate is around 70 percent. Public Health Delegate Appeals for Flu Vaccination
District Public Health officials in Portalegre today called on people to get vaccinated against the flu, they reminded them that during the winter hundreds of people die in Portugal due to the flu and the cold weather. In the Portalegre district, the vaccination rate against the flu is around 70 percent; there is enough free vaccine for the population, particularly citizens aged 65 and over, all chronic and immunocompromised patients, along with all health professionals and nursery and nursing staff working with them
Oncologist Umberto Tirelli says that for all healthcare professionals getting a flu jab is a moral obligation
" Every year we see an embarrassingly low percentage of healthcare workers, usually under 20%, getting vaccinated against influenza, which is, now about to break out here in Italy". Oncologist Umberto Tirelli said that non-vaccinated healthcare workers working in the UK healthcare system are forced to submit a justification for their decision. Adding that it is noteworthy that in Great Britain almost two-thirds of the health personnel are already vaccinated against the flu.
Vaccines and social responsibility: the LEN example to prevent the spread of influenza
A Parma-based cooperative is reaching out to companies and society to promote the benefits of flu vaccination and prevention by actively campaigning alongside AUSL to show businesses and others the financial benefits
Influenza immunization: nurses need more than ever to be on the front line
In France, while nurses' mistrust of the influenza vaccination is increasing (only 10% of them are vaccinated against 25% of doctors), a government decree has expanded the requirements for nursing skills in this area and the National Order of Nurses (ONI) is engaged in a campaign to convince nurses to vaccinate themselves against the flu and to work to get their patients vaccinated
Government must take action to protect Americans from 21st century health threats
The U.S. continues to face significant health security threats — from bioterrorism to natural threats from pandemic influenza and antibiotic resistant bacteria. Significant progress has been made to build the right structure, partnerships, and products needed to save lives and protect Americans from many of these threats. Over the past decade, BARDA and its private sector partners have shepherded 34 products through development to receive approval by the FDA
New tools to handle infectious disease outbreaks
As flu season kicks off, the Canadian Centre for Occupational Health and Safety (CCOHS) has released a microsite full of tools and resources to help workplaces and communities minimize the impact of flu and infectious disease outbreaks. The Flu and Infectious Disease Outbreaks site provides information, tips and resources intended to help keep workplaces operational and people healthy, working and thriving during a widespread flu outbreak or a pandemic
Seasonal Flu Activity Up Across The U.S.
According to the Centers for Disease Control and Prevention, seasonal influenza activity is increasing in the U.S. The flu season officially started last month, and already, more than a dozen states, including Maryland, are reporting flu activity. While the flu season can be unpredictable, a flu vaccination is your best form of defense
Flu spread expected moderate as season kicks off
While some experts in Lebanon forecast a moderate season in terms of how contagious the flu turns, local healthcare workers still suggest getting a flu vaccination. There are two major categories of influenza vaccine, a trivalent formulation, which contains antigens from two influenza A viruses (H3N2 and H1N1) and one influenza B virus. More recently a quadrivalent formulation has been created which contains the three antigens above as well as an additional influenza B antigen
Vaccination: The Cornerstone of Occupational Health, Patient Safety
The cornerstone of occupational health this time of year continues to be influenza vaccination, but compliance remains an ongoing challenge. To estimate flu vaccination coverage among healthcare personnel in the U.S. during the last influenza season, the CDC conducted an opt-in Internet panel survey of 2,438 HCP. The survey revealed that vaccination coverage continued to be higher among HCP working in hospitals (92.3 percent) and lower among HCP working in ambulatory (76.1 percent) and long-term care (LTC) (68 percent) settings
Killer flu to hit BRITAIN? Expert warns UK at risk of 'severe' pandemic
Experts fear that Australia’s deadly flu season – which killed 57 people, compared with 27 last year – could pave the way for trouble in Britain this winter. Unpredictable mutations in the virus occur so rapidly that vaccinations against the killer illness become outdated within a matter of years
28,000 people have been vaccinated against flu in the Algarve for free
In Portugal, since the beginning of the influenza vaccination campaign, between October 1 and November 12, approximately 28,000 vaccines have been administered free of charge at the Algarve Health Centers for free, which, when compared with the same period last year, represents an increase of 1,000 people vaccinated for free, the ARS Algarve reported
Burden of disease
First flu-related death of 2017-18 season reported in Clark County
A child has died from the flu, marking the first flu-related death in Clark County, Nevada, in the 2017-2018 season. SNHD reports that there were a total of 78 confirmed influenza cases reported in Southern Nevada. The percentage of emergency department visits is considered to be at a 'warning level.' About 43 percent of emergency department visits for influenza-like illness were children younger than five years old