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"Seqirus Media Monitoring" 11th Aug 2017

News Highlights
Seqirus announces major increase of influenza vaccine output Seqirus recently announced a major milestone in the fight against pandemic threats in the United States, consisting of a four-fold increase in seasonal influenza vaccine creation over two years
GPs told to prescribe Tamiflu by public health chiefs against WHO advice In the UK, GPs should continue to prescribe Tamiflu even though it was downgraded earlier this year by the World Health Organisation, Public Health England has said
Vaccine funding must continue — the health of American children is at stake Childhood vaccination programs in the US are on the chopping block in the current administration’s 2018 budget proposal and various proposals to replace the Affordable Care Act
Catching the Flu Can Trigger an MS Relapse by Activating Glial Cells, Study Suggests A flu infection can provoke relapses in MS patients by activating glial cells that surround and protect nerve cells. In a study in mice, scientists found that activated glial cells increase the levels of a chemical messenger in the brain that, in turn, triggers an immune reaction and, potentially, autoimmune attacks
Inhibitory activity of selenium nanoparticles functionalized with oseltamivir on H1N1 influenza virus In a new study, OTV surface-modified SeNPs with superior antiviral properties and restriction on drug resistance were synthesized; the results demonstrate that Se@OTV is a promising efficient antiviral pharmaceutical for H1N1
Seqirus
Seqirus announces major increase of influenza vaccine output
Seqirus recently announced a major milestone in the fight against pandemic threats in the United States, consisting of a four-fold increase in seasonal influenza vaccine creation over two years
Does CSL Limited’s Stock-Based Salary Match Market Standards?
A look at CSL CEO Paul Perreault’s stock-based compensation and at the performance of CSL over the last 2 years which concludes that his salary “seems reasonable in terms of current market standards”
Pandemic Influenza News
H9N2 avian influenza case reported in Chinese baby
A 2-month old girl who lives in Guangdong Province, China was confirmed positive for A(H9N2) influenza in June, according to the World Health Organization, becoming the third case in China this year
Eritrea, Tanzania: Only African countries ready to face global pandemics
Only two African countries, Eritrea and Tanzania, are fully prepared to face a global pandemic according to a World Bank sponsored report; bird flu is giving economies especially in southern Africa region some tough time
Industry News
Vaccine funding must continue — the health of American children is at stake
Childhood vaccination programs in the US are on the chopping block in the current administration’s 2018 budget proposal and various proposals to replace the Affordable Care Act
New findings support decision not to use FluMist vaccine
Findings published in The New England Journal of Medicine supported federal recommendations that the FluMist Quadrivalent influenza vaccine not be used on patients in the U.S. because studies showed that it was ineffective at protecting patients against the 2009 pandemic strain of A(H1N1)pdm09
Doctors join trial on University of Sunshine Coast’s new flu rapid detection system
Australian doctors are working with the University of the Sunshine Coast (USC) Clinical Trials Centre on a new rapid detection device for flu, known as the ellume:lab Flu A+B Test, including a tool for taking a nasal sample, an eStick to detect flu antigens in the sample and a phone-sized analysis unit
GPs told to prescribe Tamiflu by public health chiefs against WHO advice
In the UK, GPs should continue to prescribe Tamiflu even though it was downgraded earlier this year by the World Health Organisation, Public Health England has said
Plymouth dispenses Vaccine Group
University of Plymouth spinout Vaccine Group will target pathogens such as avian flu, Ebola virus, Mers, Sars and Rift Valley fever, initially focusing on vaccines for animals to prevent viruses crossing over to humans
Gujarat government upgrades stock of swine flu drug to ensure consistent supply of medicines
Gujarat government has replenished stocks of swine flu drug from the earlier stock of 20,000 capsules to 65,000 capsules as a step towards maintaining consistent supply of medicines to the patients
Altimmune Announces Second Quarter 2017 Financial Results and Provides Corporate Update
Altimmune announced financial results for the three- and six-months months ended June 30, 2017, including increases in manufacturing costs in preparation for the NasoVAX Phase 2 trial
Can Novavax Stage A Comeback In Q4? One Analyst Thinks So
Following the presentation of encouraging pre-clinical data from Novavax's nanoparticle influenza vaccine, Ladenburg Thalmann upgraded shares of the company
Academic studies
Previous maternal influenza vaccine does not weaken newborn benefit
Receipt of influenza vaccine the previous year predicts higher baseline antibody titers and decreased peak antibody responses against all influenza strains in pregnant women, according to a study
Seasonal H3N2 and 2009 Pandemic H1N1 Influenza A Viruses Reassort Efficiently but Produce Attenuated Progeny
A new study has evaluated the potential for viruses of the 2009 pandemic H1N1 (pH1N1) and seasonal H3N2 lineages to re-assort under experimental conditions Seasonal H3N2 and 2009 Pandemic H1N1 Influenza A Viruses Re-assort Efficiently but Produce Attenuated Progeny
Catching the Flu Can Trigger an MS Relapse by Activating Glial Cells, Study Suggests
A flu infection can provoke relapses in MS patients by activating glial cells that surround and protect nerve cells. In a study in mice, scientists found that activated glial cells increase the levels of a chemical messenger in the brain that, in turn, triggers an immune reaction and, potentially, autoimmune attacks
Inhibitory activity of selenium nanoparticles functionalized with oseltamivir on H1N1 influenza virus
In a new study, OTV surface-modified SeNPs with superior antiviral properties and restriction on drug resistance were synthesized; the results demonstrate that Se@OTV is a promising efficient antiviral pharmaceutical for H1N1
Functional Evolution of Influenza Virus NS1 Protein in Currently Circulating Human 2009 Pandemic H1N1 Viruses
A new study shows that the NS1 protein from currently circulating pH1N1 viruses has evolved to encode 6 amino acid changes with respect to the original protein
Interplay of PA-X and NS1 Proteins in Replication and Pathogenesis of a Temperature-Sensitive 2009 Pandemic H1N1 Influenza A Virus
A new study evaluated the combined effect of PA-X- and NS1-mediated inhibition of general gene expression on virus pathogenesis, using a temperature-sensitive, live-attenuated 2009 pandemic H1N1 IAV (pH1N1 LAIV)
Data Support ACIP Decision Not to Use Live Attenuated Flu Vaccine
During the 2015 to 2016 season, influenza vaccines reduced the risk of flu, but the live attenuated vaccine was ineffective among children 2 to 17 years of age, according to a study published in the New England Journal of Medicine
Pediatric influenza news
Meijer to host BTS flu-shot campaign
In the US, Meijer pharmacies across the Midwest are holding Back to School Immunization Events this weekend to help families guard against the flu before classes start
Medical Experts Speak about The Importance of Vaccinations During Immunization Awareness Month
As part of National Immuniza¬tion Awareness Month, paediatricians are reminding parents about the importance of vaccinations; the flu causes more deaths each year than any other vaccine-preventable disease, according to the CDC
Flu preparations underway for winter
In Scotland, preparations are already underway for winter as the local health board prepare for the school flu jab programme; the vaccine will be delivered in the form of a nasal spray
Over 65’s influenza news

No News Recorded

General Influenza News
Less than a quarter of Nigerian children complete vaccination — Survey
Only about 23 per cent of children in Nigeria have received all recommended vaccines between 2016 and 2017, the Multi Indicator Cluster Survey report has revealed
Romania’s Government adopts draft bill on vaccination
The Romanian Government has adopted the draft bill on the organization and financing of vaccination of the general population
Co-producer of controversial film Vaxxed touring NZ
The co-producer of a controversial anti-vaccine documentary who was banned from Australia because she might be a risk to the community is touring New Zealand
Zimbabwe: Avian Flu Threatens Poultry Production
Poultry production in Zimbabwe and its neighbours is under threat from the outbreak of the Highly Pathogenic Avian Influenza (HPAI), the Food and Agriculture Organisation has warned
Burden of disease
Better prepared for swine flu, but treatment gaps remain
In India, health authorities are better prepared to tackle the rise in swine flu cases this year, but treatment gaps remain on the ground, as chemists point to shortages in the suspension form of oseltamivir for children
CQ's huge flu spike, more than 60 cases in 1 week
In Australia, a local pharmacist is encouraging people to get vaccinated against the flu after a spike in cases this winter
Hong Kong’s summer flu season ‘could last for three more weeks’
In Hong Kong, the summer flu season could last for three more weeks despite a recent drop in local flu activity, a public health expert has said
Flu activity remains high in parts of Southern Hemisphere
The World Health Organization released their weekly global flu update, noting that activity remained high in the temperate zone of the Southern Hemisphere and in some countries in Southeast Asia. Influenza A (H3N2) is still the predominate strain worldwide
Flu Queensland: State Government enacts hospital management plan
The Queensland Government is poised to enact a hospital management plan, after a huge spike in southeast Queensland influenza cases; Royal Brisbane and Women’s Hospital emergency specialist Dr Rosengren said the problem was not that the vaccine wasn’t working, it was the people who didn’t get the jab