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"Seqirus Media Monitoring" 15th Aug 2017

News Highlights
How an acquisition has quadrupled production for Seqirus in Holly Springs Two years out from parent company CSL’s acquisition of the global influenza vaccine business of Novartis for $275 million, Seqirus continues to ramp up production at its Holly Springs site and has quadrupled production in seasonsal influenza vaccine output in just two years
Government moves to prevent bird flu jump to humans Three days after confirming an avian flu outbreak in the Philippines, government agencies are scrambling to keep the virus from spreading and especially from jumping to humans, starting with a nationwide inspection of poultry farms
Hemispherx Human Safety Study of Intranasal Ampligen® with Influenza Vaccine Shows Ampligen was Generally Well-Tolerated Hemispherx BioPharma shares went up 10% after the drug maker commenced full data analysis of an intranasal human safety study of Ampligen plus FluMist known as AMP-600; in the study, Ampligen was generally well-tolerated when administered intranasally with a live-virus influenza vaccine
Virulence factor made by influenza virus is potential target for vaccine drug development A new study describes how NS1, a protein produced by influenza A viruses, suppresses the body's immune responses to viral infection; there is potential to develop a live attenuated vaccine based on an engineered influenza A virus lacking NS1 and to design antiviral drugs that target NS1
Natco to unveil 8-10 branded formulations Natco plans to extend the Tamiflu franchise with the launch of the suspension version
The insanity surrounding Tamiflu – a supposed miracle Tamiflu was meant to be a coveted, efficient drug, but the WHO has now downgraded it to a non-essential medicine as its efficiency might not be better than simply washing one’s hands
Seqirus
How an acquisition has quadrupled production for Seqirus in Holly Springs
Two years out from parent company CSL’s acquisition of the global influenza vaccine business of Novartis for $275 million, Seqirus continues to ramp up production at its Holly Springs site and has quadrupled production in seasonsal influenza vaccine output in just two years
Pandemic Influenza News
Western Cape Department of Agriculture on possible incidence of bird flu in Western Cape
The Western Cape Department of Agriculture is investigating possible incidences of Highly Pathogenic Avian influenza (HPAI), type H5N8, on two ostrich farms in the Heidelberg area
Flu vaccine for poultry industry workers
In the Philippines, the Health Department is providing free flu vaccine to poultry owners, workers and their relatives to avoid infection in response to the recent outbreak of the Avian Influenza Type A Subtype H5
Government moves to prevent bird flu jump to humans
Three days after confirming an avian flu outbreak in the Philippines, government agencies are scrambling to keep the virus from spreading and especially from jumping to humans, starting with a nationwide inspection of poultry farms
Natco to unveil 8-10 branded formulations
Natco plans to extend the Tamiflu franchise with the launch of the suspension version
Industry News
The insanity surrounding Tamiflu – a supposed miracle
Tamiflu was meant to be a coveted, efficient drug, but the WHO has now downgraded it to a non-essential medicine as its efficiency might not be better than simply washing one’s hands
Where we stand with influenza vaccines for the 2017-18 season – Paul Ehrlich Institut
The Paul-Ehrlich-Institute has so far released 8 million doses of flu vaccine, but not all are available in pharmacies: Influvac was not available last week, nor were Fluad 2017/2018, Conceptual, Vaxigrip, Vaxigrip tetra and Xanaflu; Influsplit tetra and Afluria seem to be at least partly available
BiondVax gets IIA funding for flu vaccine candidate
BiondVax announced that the Israel Innovation Authority agreed to fund up to 40% of a 2.7 million new Israeli shekels (~$750,000) budget towards ongoing development of M-001, the company’s universal flu vaccine candidate
Hemispherx Human Safety Study of Intranasal Ampligen® with Influenza Vaccine Shows Ampligen was Generally Well-Tolerated
Hemispherx BioPharma shares went up 10% after the drug maker commenced full data analysis of an intranasal human safety study of Ampligen plus FluMist known as AMP-600; in the study, Ampligen was generally well-tolerated when administered intranasally with a live-virus influenza vaccine
Why analysts think Novavax's flu vaccine could be a big deal
Preclinical data provided a boost to Novavax's shares last week
Academic studies
Flu “patch” as effective as shots, preferred by patients
A microneedle flu patch has been developed that does not require refrigeration or sharps disposal, could be mailed to patients for self-administration and may appeal to individuals who hate shots
With proper tools, pharmacists increase adult vaccination rates
With access to the right tools, eight community pharmacies in Washington State who were part of Project IMPACT Immunizations increased the number of vaccines administered by 41.4% over a 6-month period
Pharmacist Immunization Policies Boost Flu Vaccine Uptake
A study focusing on whether changes and policy at the state level affect influenza virus vaccine uptake found that the odds that an adult would receive the flu shot increased by 7.8% in states that allowed pharmacists to be immunizers
Virulence factor made by influenza virus is potential target for vaccine drug development
A new study describes how NS1, a protein produced by influenza A viruses, suppresses the body's immune responses to viral infection; there is potential to develop a live attenuated vaccine based on an engineered influenza A virus lacking NS1 and to design antiviral drugs that target NS1
Pediatric influenza news
One-fourth of parents, patients deem teen vaccination nonessential
A recent survey conducted by Unity Consortium in the U.S. shows that nearly one in four teenagers and one in four parents believe that vaccinations are more important for infants and that 34% of teenagers are unaware of the benefits of adolescent vaccination
Study Finds Parents of Teens Don't Know Vaccination Schedules
Most parents of teenagers believe (wrongly) their children have all the vaccinations needed for their age, despite national data suggesting otherwise
Small Drops in Vaccination Rates Could Cause Big Increases in Health-Care Costs
Even small decreases in the rates of childhood immunizations can result in significant cost increases to the health-care system in the U.S., according to a recent study
Flu vaccine coming to East Dunbartonshire schools
In Scotland, school immunisation teams are getting ready to offer the flu vaccine to almost 9,000 East Dunbartonshire primary school pupils
Over 65’s influenza news

No News Recorded

General Influenza News
Film Arcade, Gravitas Nab Doc About Controversial Anti-Vaccination Figure
Documentary ‘The Pathological Optimist’, about leading anti-vaccination figure Dr. Andrew Wakefield, offers a character study of the controversial doctor, one of 13 co-authors of a notorious 1998 paper in The Lancet that suggested a link between vaccines and autism
Health experts issue Haj advisory
All Haj travellers are advised to get their mandatory meningococcal vaccine and all other recommended vaccines for infectious diseases such as influenza, pneumonia, meningitis yellow fever and polio
Liability is limited in vaccine-related injuries
The number of adults claiming injury from vaccine administration is on the rise, but providers rarely run the risk of liability; the shift seems to coincide with more widespread uptake of the flu vaccine, which is also the vaccine most commonly alleged to cause injury
Study: Patients more likely to get the flu shot when it's available at retail
Making influenza immunizations available through retail pharmacy increases the odds that a patient will get the flu shot, according to an article published in Clinical Therapeutics last week
Burden of disease
Swine flu now perennial threat
The H1N1 Swine Flu virus has mutated again, and now the disease isn’t seasonal anymore. This year, 15,121 people in India have fallen prey to the disease, which has claimed 736 lives. Dr Soumya Swaminathan, Director General, Indian Council of Medical Research, confirmed that the virus has mutated and will now affect people all year round
Hospitals hit hard by flu
Hospitals in Northern NSW, Australia, have been swamped in recent weeks following a spike in the number of preventable flu cases; North Coast Public Health director Paul Corben said people should still get vaccinated to avoid becoming seriously ill
Its officials — H1N1 pandemic has gripped UP
Alarmed over the surge of H1N1 cases, the Uttar Pradesh government declared the disease as pandemic, having formally accepted that H1N1 is prevalent in districts of the state
Flu peak passes after claiming 339 lives
In Hong Kong, three children and 336 adults have died during the summer flu peak season, one of the worst in recent years, but the Hospital Authority announced the peak period is subsiding
Aussies suffering through worst flu season on record
Doctors are recommending people get flu shots as Australia suffers through the worst flu season since authorities started keeping records in 2012
Mainland tourists cancel visits to Hong Kong, comparing summer influenza season to SARS outbreak
According to the latest Flu Express published by the Centre for Health Protection in Hong Kong, although the local flu activity remains elevated – it has decreased significantly. Some of the Mainland media and internet users have been spreading rumours– claiming the summer flu in Hong Kong is comparable to SARS in 2003