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"Seqirus Media Monitoring" 27th Sep 2017

News Highlights
Influenza; list of vaccines authorized by the Aifa for the 2017/2018 season The Italian Drug Agency (AIFA) has released the list of influenza vaccines for the 2017/2018 season, including Afluria, Agrippal S1, Fluad and Influpozzi by Seqirus; Batrevac and Influvac S by BGP Products (Mylan group); Fluarix Tetra by GlaxoSmithKline, Vaxigrip and Vaxigrip Tetra by Sanofi Pasteur
A Flu Med with Meager Benefits With the flu season threatening, the FDA has just approved an IV treatment for the flu for children as young as 2 years old. Rapivab (peramivir) was first approved for adults by the FDA in late 2014. It joins Tamiflu and Relenza (zanamivir) as questionably useful drugs that shorten a bout with the flu by a scant 12 to 22 hours
Avian influenza (H5N3) outbreak in the French region of Maine-et-Loire, 8,500 turkeys to be slaughtered In the Maine-et-Loire region of France, an outbreak of H5N3 avian influenza has been confirmed on a turkey farm, where 8,500 turkeys are to be slaughtered to avoid the virus spreading further
Clusters of Human Infections With Avian Influenza A(H7N9) Virus in China, March 2013 to June 2015 Limited person-to-person transmission is likely to have occurred on multiple occasions since the H7N9 virus was first identified. However, these transmission events represented a small fraction of all identified cases of H7N9 human infection, and sustained person-to-person transmission was not documented
Avian flu virus found in bird excretions in rural city A South Korean provincial government said that the avian influenza virus had been found in bird excretions in the southern part of the country. The government of North Gyeongsang Province said the H7N7 strain of avian influenza was detected in the excretions of wild birds
Medicago Announces Phase 3 Study of VLP Quadrivalent Influenza Vaccine Medicago announced the start of a Phase 3 efficacy study for its seasonal quadrivalent influenza vaccine (QIV) candidate. This study is in support of Medicago's flu program and expected launch of the vaccine in time for the 2020 influenza season in Canada, USA and Europe
Dr. Marie-Paule Kieny Appointed To The Human Vaccines Project Board Of Directors The Human Vaccines Project has appointed Dr. Marie-Paule Kieny to its Board of Directors. Dr. Kieny is currently Director of Research at Institut National de la Santé et de la Recherché Médicale (INSERM) where she connects INSERM with the international health research community, and has held several positions at the World Health Organization
Biochemists discover mechanism that helps flu viruses evolve Flu viruses' rapid evolution relies in part on hijacking some of the cellular machinery of the infected host cell -- a group of proteins called chaperones, which help other proteins fold into the correct shape. When viruses are unable to get help from these proteins, they do not evolve as rapidly, research shows
Australian Biotech Leads New Hope for Influenza Control Australian researchers could pave the way for a new approach to influenza control with positive results presented from preclinical studies demonstrating the effectiveness of anti-influenza drug compounds to prevent and treat influenza infections
Pharmacists urge flu jabs as ‘worst epidemic in 50 years’ heads to Ireland and UK from Australia this winter Irish pharmacists are urging the public to get flu jabs this winter after Australia suffered a deadly outbreak which killed eight pensioners in a single care home
Experts fear flu vaccine less effective Experts warn the flu vaccine's effectiveness may have dropped below 40 per cent this year. Flaws in its manufacturing and design have become apparent. The current vaccine is grown in eggs - but scientist are now concerned that this may cause the vaccine to mutate, rendering it less effective
Seqirus mentions
Influenza; list of vaccines authorized by the Aifa for the 2017/2018 season
The Italian Drug Agency (AIFA) has released the list of influenza vaccines for the 2017/2018 season, including Afluria, Agrippal S1, Fluad and Influpozzi by Seqirus; Batrevac and Influvac S by BGP Products (Mylan group); Fluarix Tetra by GlaxoSmithKline, Vaxigrip and Vaxigrip Tetra by Sanofi Pasteur
In Our Opinion: Don't put off getting your flu shot this year
This year, there is an enhanced vaccine for senior citizen: the FLUAD shot contains four times the amount of antigen as the regular one and boosts immune response following vaccination. A study by the CDC showed that it reduced cases of the flu by 24 percent for seniors compared to the standard vaccine
A Flu Med with Meager Benefits
With the flu season threatening, the FDA has just approved an IV treatment for the flu for children as young as 2 years old. Rapivab (peramivir) was first approved for adults by the FDA in late 2014. It joins Tamiflu and Relenza (zanamivir) as questionably useful drugs that shorten a bout with the flu by a scant 12 to 22 hours
Do you know what is contained in a vaccine and why?
An explanation of the additives to be found in vaccines; Fluad was licensed by the FDA in November 2015 as the first seasonal influenza vaccine containing a novel adjuvant. Fluad is licensed for people 65 years of age or older but may become available for children
Alberta won't offer nasal spray this flu season
Alberta Health Services held a news conference where health officials announced Fluad, which is for seniors, and FluMist, used on children, will no longer be available. Only seniors living in long-term care or in supported living facilities will have access to Fluad
Pandemic Influenza News
Avian influenza (H5N3) outbreak in the French region of Maine-et-Loire, 8,500 turkeys to be slaughtered
In the Maine-et-Loire region of France, an outbreak of H5N3 avian influenza has been confirmed on a turkey farm, where 8,500 turkeys are to be slaughtered to avoid the virus spreading further
Avian flu has killed 21,342 people
Since 2004, the H5N1 virus has caused the death of 21,342 people according to FAO representative to Senegal Réda Lebtahi
Clusters of Human Infections With Avian Influenza A(H7N9) Virus in China, March 2013 to June 2015
Limited person-to-person transmission is likely to have occurred on multiple occasions since the H7N9 virus was first identified. However, these transmission events represented a small fraction of all identified cases of H7N9 human infection, and sustained person-to-person transmission was not documented
Avian flu virus found in bird excretions in rural city
A South Korean provincial government said that the avian influenza virus had been found in bird excretions in the southern part of the country. The government of North Gyeongsang Province said the H7N7 strain of avian influenza was detected in the excretions of wild birds
Industry News
Medicago Announces Phase 3 Study of VLP Quadrivalent Influenza Vaccine
Medicago announced the start of a Phase 3 efficacy study for its seasonal quadrivalent influenza vaccine (QIV) candidate. This study is in support of Medicago's flu program and expected launch of the vaccine in time for the 2020 influenza season in Canada, USA and Europe
Vulnerable groups may be put at risk
Many German doctors are angry about not being able to offer the best prices for flu vaccinations for four strains of flu as insurers holdback on agreed pay-outs for the vaccine protection needed
Dr. Marie-Paule Kieny Appointed To The Human Vaccines Project Board Of Directors
The Human Vaccines Project has appointed Dr. Marie-Paule Kieny to its Board of Directors. Dr. Kieny is currently Director of Research at Institut National de la Santé et de la Recherché Médicale (INSERM) where she connects INSERM with the international health research community, and has held several positions at the World Health Organization
CDC does not recommend flu mist as flu shot alternative this season
In Honolulu, the flu season has started. The CDC says now is the time to get the flu vaccine, but to get the shot and not FluMist
Flu Vaccines for the 2017/2018 season? What do they contain when can we get vaccinated?
In Poland, two flu vaccines are recommended for the 2017/2018 flu season: Sanofi Pasteur’s Vaxigrip Tetra and BGP Products’ Influvac
Academic studies
Biochemists discover mechanism that helps flu viruses evolve
Flu viruses' rapid evolution relies in part on hijacking some of the cellular machinery of the infected host cell -- a group of proteins called chaperones, which help other proteins fold into the correct shape. When viruses are unable to get help from these proteins, they do not evolve as rapidly, research shows
Australian Biotech Leads New Hope for Influenza Control
Australian researchers could pave the way for a new approach to influenza control with positive results presented from preclinical studies demonstrating the effectiveness of anti-influenza drug compounds to prevent and treat influenza infections
Pediatric influenza news
Lib Nat government would fund free flu vaccines
Victoria’s state Opposition has committed to free flu vaccines for all kids, should it win the next state election. Shadow Minister for Health Mary Wooldridge announced that a Liberal Nationals Government would provide up to $7 million over four years for free voluntary flu vaccinations for all Victorian children between the ages of six months and five years old
Half of Cornish children not vaccinated against flu virus are at risk of serious illness or death
Nearly half of Cornish children have not been vaccinated against the flu virus and are at risk of serious illness or death, new figures have revealed. Figures from Public Health England revealed 363 two-to-four year olds in the region considered at particular risk from flu due to existing health conditions, went unvaccinated in 2016-17
Over 65’s influenza news
Flu shot effectiveness boosted by listening to your favourite song, researchers find
The researchers found a link between those who recorded a good mood throughout the six-week observation period, and levels of flu protection detected in a person's blood four months later. But there was an even stronger link found between the jab's effectiveness and being in a good mood on the day of the vaccine itself.
Pharmacists urge flu jabs as ‘worst epidemic in 50 years’ heads to Ireland and UK from Australia this winter
Irish pharmacists are urging the public to get flu jabs this winter after Australia suffered a deadly outbreak which killed eight pensioners in a single care home
Maybe more adults should get the high-dose flu shot
Expanding the high-dose influenza vaccine recommendation to include middle-aged adults with chronic health conditions may make economic sense and could save lives. The findings of a new study call for clinical trials of the high-dose and new recombinant trivalent influenza vaccines in 50- to 64-year-old adults with chronic illnesses, to determine if they offer better protection than the currently recommended standard-dose quadrivalent vaccine
General Influenza News
Experts fear flu vaccine less effective
Experts warn the flu vaccine's effectiveness may have dropped below 40 per cent this year. Flaws in its manufacturing and design have become apparent. The current vaccine is grown in eggs - but scientist are now concerned that this may cause the vaccine to mutate, rendering it less effective
Healthy people are dying from the flu and doctors say it’s time to make the influenza vaccine free
The flu vaccine should be provided free for everyone as the death toll mounts from this year’s killer flu outbreak doctors say. The government is also under pressure to buy better quality flu vaccines with experts claiming the cheap as chips version we use does not properly protect the elderly
16th Annual Meeting on Influenza
Influenza 2018 will attract a large group of scientists and researchers round the globe. This two-day Conference will address key issues concerning Influenza strains, pandemics, epidemics and its impacts in the broader context of Epidemiology, Pathology, Virology, Clinical microbiology and Immunology
CDC highlights security programs against infectious disease
Over the past decade alone, epidemiologists have been kept busy responding to infectious disease outbreaks with enormous global health and economic impacts. To highlight its efforts to contain and alleviate outbreaks, the CDC will publish a special supplement to its journal Emerging Infectious Diseases discussing programs created to effectively respond to them
Canberra mother dies after contracting flu
In Australia, ACT health minister Meegan Fitzharris expressed her sympathy to the family of a young mother killed by the flu. She said that "we also need to talk about the federal government's role in making sure that the flu vaccine is readily available to people that may already be vulnerable or people working particularly in healthcare settings or in other workplaces where there may be vulnerable people"
What is Aussie Flu? Doctor Chris discusses KILLER outbreak coming to UK on This Morning
TV Dr Chris talks about the flu outbreak in Australia and what it means for the UK, and speculates that “We have a flu vaccine for children over here - the nasal spray - which they don't have in Australia, which may be why it's been so bad over there"
Killer ‘Aussie flu’ H3N2 is heading to the UK
Professor Robert Dingwall, a public health expert from Nottingham Trent University, thinks it’s inevitable the Aussie flu will make its way to the UK
Vaccination: Minister allays fears
Minister for Health and Family Welfare K.R. Ramesh Kumar has allayed fears among some sections of the society that vaccination could lead to undesirable consequences
Burden of disease
Flu season has arrived in Colorado
It may only be September, but already, flu season is taking its toll on Colorado. As of Tuesday, 20 Coloradans have been hospitalized with Type A Influenza, since Aug. 1, when the state department of health begins tracking "flu season"
Reporting mismatch: Six swine flu deaths in Delhi but 31 alone in a single hospital
A total of 2,755 cases of swine flu have been reported from Delhi till September 17, according to the country-wide data released by IDSP. The number of cases is likely to be much higher as swine flu causes symptoms like fever, cold and cough and very few need hospital admission