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"Seqirus Media Monitoring" 29th Sep 2017

News Highlights
The thinking process behind biopharma companies’ outsourcing management Among the biopharma executives making presentations at this year’s Drug Development Forum was Karen Gardner, senior director of clinical development operations at CSL’s vaccines subsidiary Seqirus. She says entering into an outsourcing partnership is buying a multidimensional service. “It’s a component of people, of process and of work that needs to be done and when”
Seasonal Influenza: What is the most effective vaccine? New results presented at the European Scientific Working Group on Influenza (ESWI) Congress in Riga indicate that the adjuvant vaccine produces a better immune response against influenza in the population over 65 than the non-adjuvanted vaccine
U.S. Health Officials Urge Annual Influenza Vaccination for All The NFID, along with public health and medical organizations, urged the public to follow the CDC recommendation that everyone age six months and older be vaccinated against influenza. Three FDA-approved influenza antiviral drugs are also recommended for use in the U.S.: oseltamivir (generic version or Tamiflu), zanamivir (Relenza), and peramivir (Rapivab)
This Sinister Virus Could Cause the World's Next Flu Pandemic H7N9 avian influenza is emerging as the virus most likely to cause the next flu pandemic. While it’s not so adept at spreading from human to human, it is potent, better adapted to our respiratory tracts than H5N1 and increasingly prevalent in people. Known to be circulating only within China, H7N9 has been mutating in sinister ways this past year, putting scientists on alert
CEVA Animal Health Lab produces H5N8 vaccine In France, CEVA Animal Health Labs have produced a H5N8 vaccine which seems efficient and would not be used systematically in birds but could prove useful during outbreaks
Scripps Research-led study points to new flu drugs New and more powerful drugs to stop influenza may be possible, according to a study by scientists from The Scripps Research Institute and Janssen Research & Development, a unit of Johnson & Johnson. The study exploits a vulnerable site on the flu virus that existing drugs such as Tamiflu don’t target
Flu vaccine not as effective this year Melbourne-based biotech Aus Bio is undertaking preclinical research into a drug it says will need to be taken only once every 12 days to prevent the flu (Tamiflu is taken twice a day). University of Melbourne virologist Professor Lorena Brown said the drug compounds would change the shape of the influenza virus, so it was no longer infectious
Roughly 59% of children vaccinated against flu last season Influenza vaccination rates for children under age 2 years are meeting national goals but fall short for older children, new Centers for Disease Control and Prevention data show
Older Siblings a Risk Factor for Serious Flu Infections in Infants Small children are significantly more at risk of serious illness from influenza if they have older brothers or sisters, new research has shown. Parents were told they can help protect their young children by getting older offspring vaccinated
CDC launches LINE 'chatbot' to provide flu vaccination info Taiwan's Centers for Disease Control launched an artificial intelligence "chatbot" on social messaging app LINE to provide information and answer questions about flu vaccination
WHO swaps out H3N2, B strains in Southern Hemisphere flu vaccine At their meeting in Melbourne, Australia, WHO vaccine advisors today recommended changing two of three components for trivalent vaccines that pharmaceutical companies will produce for the Southern Hemisphere's 2018 flu season
Flu season: Fewer than half of Americans vaccinated, officials call for nearly everyone to get a shot Fewer than 50 percent of all Americans were vaccinated against the flu last season. Officials want at least 70 percent of people to get a flu shot. This season, officials say people should only get an injectable vaccine, not a nasal spray vaccine.
Seqirus mentions
The thinking process behind biopharma companies’ outsourcing management
Among the biopharma executives making presentations at this year’s Drug Development Forum was Karen Gardner, senior director of clinical development operations at CSL’s vaccines subsidiary Seqirus. She says entering into an outsourcing partnership is buying a multidimensional service. “It’s a component of people, of process and of work that needs to be done and when”
Seasonal Influenza: What is the most effective vaccine?
New results presented at the European Scientific Working Group on Influenza (ESWI) Congress in Riga indicate that the adjuvant vaccine produces a better immune response against influenza in the population over 65 than the non-adjuvanted vaccine
U.S. Health Officials Urge Annual Influenza Vaccination for All
The NFID, along with public health and medical organizations, urged the public to follow the CDC recommendation that everyone age six months and older be vaccinated against influenza. Three FDA-approved influenza antiviral drugs are also recommended for use in the U.S.: oseltamivir (generic version or Tamiflu), zanamivir (Relenza), and peramivir (Rapivab)
Pandemic Influenza News
The Colombian government stresses that the country remains free of Avian flu
In Colombia, the government has explained that the H3N2 virus, which is present in the country, is not the avian influenza virus of which Colombia remains free
This Sinister Virus Could Cause the World's Next Flu Pandemic
H7N9 avian influenza is emerging as the virus most likely to cause the next flu pandemic. While it’s not so adept at spreading from human to human, it is potent, better adapted to our respiratory tracts than H5N1 and increasingly prevalent in people. Known to be circulating only within China, H7N9 has been mutating in sinister ways this past year, putting scientists on alert
How you could help stop a flu pandemic
With international air travel at over four billion flights last year alone, stopping a flu pandemic taking hold is pretty much impossible, but the BBC Pandemic App will help a team of mathematical epidemiologists predict how a virus could spread across the UK and test what might be done to slow it down
Why Some Countries Were Harder Hit by the Pandemic Influenza Virus in 2009
A global pandemic mortality study found prominent regional mortality variations in 2009 for Influenza A(H1N1)pdm09. The study attempts to identify factors that explain why the pandemic mortality burden was high in some countries and low in others
Industry News
Novartis, Berkeley sign drug chemistry pact
Novartis’s research head expects an alliance with a University of California chemistry lab to produce drug candidates within three years as the Swiss company accelerates its hunt for new medicines
CEVA Animal Health Lab produces H5N8 vaccine
In France, CEVA Animal Health Labs have produced a H5N8 vaccine which seems efficient and would not be used systematically in birds but could prove useful during outbreaks
Four influenza vaccines have been re-registered in the Ukraine
Four influenza vaccines have been re-registered in the Ukraine – these include According to the Ministry of Health, the following vaccinations have been re-registered: INFLUWAK / INFLUVAC (Netherlands), INFLUENZA VAKSIN (China), JISI FLU / GC FLU (Korea) and VACCIHRIP / VAXIGRIP (France)
Flu Shots Aren't 100% Effective, But They're The Best Protection Available
The CDC recommends that all people six months old and up, including pregnant women, get vaccinated every year against influenza and is once again recommending against the use of FluMist
Scripps Research-led study points to new flu drugs
New and more powerful drugs to stop influenza may be possible, according to a study by scientists from The Scripps Research Institute and Janssen Research & Development, a unit of Johnson & Johnson. The study exploits a vulnerable site on the flu virus that existing drugs such as Tamiflu don’t target
Flu vaccine not as effective this year
Melbourne-based biotech Aus Bio is undertaking preclinical research into a drug it says will need to be taken only once every 12 days to prevent the flu (Tamiflu is taken twice a day). University of Melbourne virologist Professor Lorena Brown said the drug compounds would change the shape of the influenza virus, so it was no longer infectious
Academic studies
Notre Dame Engineers ‘Light Up’ Flu Detection
Detection is an important aspect of managing influenza, and a University of Notre Dame researcher has developed what he calls a simpler, faster and more scalable method that makes the virus “light up” red in a sample
Inactivated H7 Influenza Virus Vaccines Protect Mice despite Inducing Only Low Levels of Neutralizing Antibodies
Avian influenza viruses of the H7 hemagglutinin (HA) subtype present a significant public health threat, as evidenced by the ongoing outbreak of human A(H7N9) infections in China. Vaccines against H7 avian influenza viruses may be more effective than HI and virus neutralization assays suggest, and such vaccines may need other methods for evaluation
Pediatric influenza news
Roughly 59% of children vaccinated against flu last season
Influenza vaccination rates for children under age 2 years are meeting national goals but fall short for older children, new Centers for Disease Control and Prevention data show
Older Siblings a Risk Factor for Serious Flu Infections in Infants
Small children are significantly more at risk of serious illness from influenza if they have older brothers or sisters, new research has shown. Parents were told they can help protect their young children by getting older offspring vaccinated
Over 65’s influenza news
Don't Wait: Get Your Flu Shot
CDC and NFID officials said flu shots — not nasal sprays — should be given this year, and that people 65 and older and those with compromised immune systems can benefit from a high-dose shot
What you should know about flu vaccinations (Robert Koch Institute advice)
The next flu season is approaching, and particularly vulnerable people, such as the chronically ill, should be vaccinated against influenza in good time
General Influenza News
Influenza returns to Central Alberta
Flu season is coming, and Alberta Health Services says Central Albertans can fight back by getting immunized starting Oct. 23. Vaccine is available free to all Albertans six months of age and older through Alberta Health Services clinics, pharmacies and physicians
CDC launches LINE 'chatbot' to provide flu vaccination info
Taiwan's Centers for Disease Control launched an artificial intelligence "chatbot" on social messaging app LINE to provide information and answer questions about flu vaccination
DPHSS: Get vaccinated amid flu outbreak
On Guam, in light of an ongoing flu outbreak, the public health department is advising residents to get vaccinated through their primary health care providers. The Department of Public Health and Social Services recently issued a press release declaring a Type A influenza epidemic
Flu epidemic: Experts explain the reasons behind Australia's bad season
Infectious Diseases experts Professor Peter Collignon from the Australian National University's Medical School, and Professor Allen Cheng from Monash University and The Alfred Hospital answer some common questions on the flu outbreak that hit Australia
WHO swaps out H3N2, B strains in Southern Hemisphere flu vaccine
At their meeting in Melbourne, Australia, WHO vaccine advisors today recommended changing two of three components for trivalent vaccines that pharmaceutical companies will produce for the Southern Hemisphere's 2018 flu season
Flu season: Fewer than half of Americans vaccinated, officials call for nearly everyone to get a shot
Fewer than 50 percent of all Americans were vaccinated against the flu last season. Officials want at least 70 percent of people to get a flu shot. This season, officials say people should only get an injectable vaccine, not a nasal spray vaccine.
Tom Price declines to comment on private jet travel, gets his flu shot
This flu season could be a bad one, and Health and Human Services Secretary Tom Price got his flu shot Thursday and urged Americans to follow his example and get vaccinated
CDC: Hospitals continue to lead field in health care worker flu vaccinations
An estimated 92% of hospital workers report receiving a flu vaccine for the 2016-17 flu season, compared with 76% of ambulatory care workers and 68% of long-term care workers, according to a survey released today by the CDC
Flu vaccination expansion needed
In Australia, Chief Medical Officer Professor Brendan Murphy said the 2017 flu vaccine was well matched to the circulating strains – yet appears to have been less effective than usual, especially in the elderly
‘People do die from flu’ warns doctor, as he encourages those at risk to get vaccinated
In the UK, a doctor has urged people to protect themselves and their loved ones from flu by making sure they are vaccinated against the potentially deadly illness
Burden of disease
The dangerous four bugs responsible for the annual flu outbreak
There are 4 bugs that can trigger a seasonal flu outbreak (H1N1, H3N2, Victoria and Yamagata viruses) and they are all knocking at the door now the cold and flu season is upon us
Swine flu found in 20 people after coming into contact with pigs at county fairs
A swine flu virus strain was detected in 20 people in Maryland who were in close contact with pigs at two county fairs. The Maryland Department of Health reports none of those infected with the influenza virus strain H3N2v has become seriously ill or been hospitalized