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"Seqirus Media Monitoring" 16th Oct 2017

News Highlights
A flu vaccine with MF59 enhancer can better protect children between six and 24 months from influenza viruses than the conventional vaccines A flu vaccine with MF59 enhancer can better protect children between six and 24 months from influenza viruses than the conventional vaccine, according to a Phase III study presented by researchers from the University of Tampere Medical School in Finland at an international conference in Riga. "For older children, there was no additional benefit," said Timo Vesikari of the University of Tampere about the study he carried out together with scientists from Finland, the US, the Philippines and Seqirus
A bird flu outbreak detected in the Netherlands An H5 type avian flu outbreak has been detected in the south of the Netherlands, and 42,000 hens will be slaughtered as a result to prevent spreading to other farms
Flu vaccine is only 40-60pc effective this winter as epidemic looms The flu jab only provides limited protection for older people against the virus - raising new fears as experts warn of a potential epidemic this winter. The vaccine currently being distributed to GPs and pharmacists is just 40pc to 60pc effective and may have had little or no effect in keeping older age groups safe from the illness last year.
NHS "fears a crisis" this winter if flu jab for elderly fails to work NHS bosses are reportedly “scared” that hospitals will be heaving this winter if there is an outbreak of heavy flu and vaccinations given to old people fail to work. They have rolled out a jabs programme for the elderly in order to stave off a crisis in its service. A review of last year’s vaccination programme found it failed to help the elderly from contracting the flu
Flu vaccination is a good investment against the potential disastrous economic risk of a flu epidemic There is a huge cost to society if we don't ensure that people are vaccinated against the flu, according to Sanofi-Pasteur VP, David Loew. Across Europe, the influenza virus is responsible for 40,000 deaths each year, well above the 25,000 deaths due to road traffic accidents
Are we prepared for the next disease outbreak? Most emerging disease threats come from variants of the bird flu virus subtypes (H5N1, H7N9, H9N2) and swine flu virus subtypes (H1N1, H3N2). The next big threat pandemic threat is likely to be from a bird flu virus, which has prompted the CDC to classify avian influenza viruses as “viruses of special concern”
Angry Poultry Farmers Threaten To Sell Infested Birds A group calling itself the Concerned Poultry Farmers within the Greater Accra Region, has warned that their members may sell unwholesome chicken to the public if the government continues to default in the payment of compensations owed them. According to the farmers, the government has failed to pay them 1.8 million Ghana cedis as compensation for the destruction of some 63 thousand live birds, which were infected with the avian influenza between 2015 and 2016
Nation bracing for tight supply of flu vaccines this winter Japan may face a shortage of influenza vaccines this winter due to a production delay. The supply volume is currently projected at some 25.28 million units, equivalent to 50.56 million doses, about 1.14 million units lower than the estimated amount used during the previous flu season and the second-lowest level in 10 years
Extra stocks of flu jab ordered amid fears of winter epidemic Additional stocks of the seasonal flu vaccine have been ordered by the HSE amid mounting fears of an epidemic this winter. Some 850,000 doses of the vaccine have been purchased - the same number as last year. However, a "contingency" supply of 100,000 doses have also been bought which the Executive "expect to draw down."
Vital influenza vaccines in short supply The shortage of influenza vaccine is causing concern among people in the valley. The drug dealers in the valley are facing erratic supply of vaccine which irks the huge rush of people who are in need of this vaccine. Sakeena Zahoor, a resident of Bohri Kadal, said she needed the vaccine for her mother. “I searched everywhere in Lal Chowk, but in vain. My mother has severe flu and dry cough, and her condition further deteriorates in winters. I need the vaccine now,” she said. “Local hospitals do not stock influenza vaccines. People need to buy it from markets.” A Srinagar-based drug distributor said they have been getting limited supply of the vaccine.
Over 250,000 will fall ill due to flu season, minister warns Over half the Maltese population, or at least 250,000, will fall ill as influenza season picks up next January, health minister Chris Fearne has warned. Fearne’s stark warning was made in an intervention during parliamentary questions on Budget day, as he prepares to launch the government’s vaccination campaign
Seqirus mentions
A flu vaccine with MF59 enhancer can better protect children between six and 24 months from influenza viruses than the conventional vaccines
A flu vaccine with MF59 enhancer can better protect children between six and 24 months from influenza viruses than the conventional vaccine, according to a Phase III study presented by researchers from the University of Tampere Medical School in Finland at an international conference in Riga. "For older children, there was no additional benefit," said Timo Vesikari of the University of Tampere about the study he carried out together with scientists from Finland, the US, the Philippines and Seqirus
Pandemic Influenza News
More than 40,000 hens slaughtered in the Netherlands following the discovery of an outbreak of avian influenza
Le Monde reports that more than 40,000 hens have been slaughtered in the Netherlands following the discovery of an outbreak of avian influenza
Are we prepared for the next disease outbreak?
Most emerging disease threats come from variants of the bird flu virus subtypes (H5N1, H7N9, H9N2) and swine flu virus subtypes (H1N1, H3N2). The next big threat pandemic threat is likely to be from a bird flu virus, which has prompted the CDC to classify avian influenza viruses as “viruses of special concern”
A bird flu outbreak detected in the Netherlands
An H5 type avian flu outbreak has been detected in the south of the Netherlands, and 42,000 hens will be slaughtered as a result to prevent spreading to other farms
Western Cape government, DAFF working to find solutions to bird flu outbreak
The Western Cape government and the Department of Agriculture, Forestry and Fisheries are continuing to work around the clock to find solutions following the bird flu outbreak. The number of confirmed cases of avian influenza in the Western Cape has risen to 50. At least 2.5 million chickens and ducks have been culled since an outbreak of bird flu occurred in the Cape
Bird flu detected at Witfield Dam
In South Africa, according to the chief state veterinarian at the Department of Agriculture and Rural Development, a dead bird at Witfield Dam tested positive for the H5N8 strain of the virus a few weeks ago. This is the only bird to have died from the virus and it remains unclear if the other wild birds are also infected
Industry News
Nation bracing for tight supply of flu vaccines this winter
Japan may face a shortage of influenza vaccines this winter due to a production delay. The supply volume is currently projected at some 25.28 million units, equivalent to 50.56 million doses, about 1.14 million units lower than the estimated amount used during the previous flu season and the second-lowest level in 10 years
Flu vaccination is a good investment against the potential disastrous economic risk of a flu epidemic
There is a huge cost to society if we don't ensure that people are vaccinated against the flu, according to Sanofi-Pasteur VP, David Loew. Across Europe, the influenza virus is responsible for 40,000 deaths each year, well above the 25,000 deaths due to road traffic accidents
Baloxavir Marboxil Demonstrates Positive Phase 3 Influenza Results
Positive phase 3 CAPSTONE-1 trial results of S-033188 (baloxavir marboxil) in otherwise healthy influenza patients were presented by Shiongoi at IDWeek 2017. Nonclinical studies of baloxavir marboxil demonstrated its anti-viral spectrum against not only seasonal influenza strains but also oseltamivir-resistant flu strains and avian flu strains, of which potential outbreak is a global public health concern
Sanofi to Inject $202m into Expanding French Production Facility to Increase Supply of Key Flu Vaccine
Sanofi said that it will invest 170 million euros into expanding its vaccine manufacturing site in the Normandy region of France as it seeks to ramp up the supply of one of its key flu vaccines, VaxigripTetra
Sanofi Pasteur to withdraw ID Flu from Korean market
Sanofi Pasteur Korea said Friday that it plans to pull their Intradermal (ID) Flu product from Korea. The decision comes after the Ministry of Food and Drug Safety dealt sales suspension of the drug for six months for failing to apply for re-examination
Doncaster LPC holds GPs to account over flu jab threats
In Doncaster, UK, local pharmacists reported a GP surgery for threatening to withhold repeat prescriptions from patients who did not get their flu jab at the practice
Academic studies

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Pediatric influenza news
Flu: Children should be vaccinated according to experts
Flu shots are recommended for the elderly and the chronically ill, and they are also appropriate for children, as explained by Finnish flu researcher Timo Vesikari from the University of Tampere during an international conference in Riga
Free flu vaccinations for pregnant women and young children in Milton Keynes
Health leaders across Milton Keynes in the UK are urging pregnant women and young children to have their free flu vaccinations as soon as possible
6 out of 10 Bristol children aren't getting freely available protection from deadly bug
Less than half of the children eligible for the flu vaccine in Bristol, UK, are receiving it, and now frustrated health chiefs are warning parents are risking their own children’s lives. Bristol has the lowest take-up levels of the flu vaccine – which is given to children as a nasal spray now, and not a jab – in the south west, and doctors are calling on parents to book their children in to the local clinic
Push Is On For Children, Adults To Get Flu Shots Sooner Rather Than Later
The American Academy of Pediatrics recommends all children receive their flu vaccinations by the end of October if possible. “In 2016 to 2017, over a hundred U.S. children died of the flu. And several thousands more were hospitalized for complications from the flu or from severe illness,” said Dr. Elissa Rubin
Nasal flu vaccine ruled ineffective by Centers for Disease Control and Prevention
Shot-sensitive patients will have fewer options this flu season after the Centers for Disease Control and Prevention pulled its recommendation of FluMist, a nasal vaccine manufactured by AstraZeneca
CDC recommends pregnant women get flu vaccination
A study from the CDC said pregnant women and their infants are at a higher risk of catching the flu. Health leaders with the Advisory Committee on Immunization Practices recommend a flu vaccine for women who are or may be pregnant during 2016-2017 flu season
Over 65’s influenza news
Flu vaccine is only 40-60pc effective this winter as epidemic looms
The flu jab only provides limited protection for older people against the virus - raising new fears as experts warn of a potential epidemic this winter. The vaccine currently being distributed to GPs and pharmacists is just 40pc to 60pc effective and may have had little or no effect in keeping older age groups safe from the illness last year.
French senior citizens reluctant to get their flu shots
In France, a report shows that less than half of people between 65 and 75 years old were vaccinated against the flu last season, despite being one of the most vulnerable age groups
NHS "fears a crisis" this winter if flu jab for elderly fails to work
NHS bosses are reportedly “scared” that hospitals will be heaving this winter if there is an outbreak of heavy flu and vaccinations given to old people fail to work. They have rolled out a jabs programme for the elderly in order to stave off a crisis in its service. A review of last year’s vaccination programme found it failed to help the elderly from contracting the flu
16 elderly people died from flu in ACT nursing homes in three months since July 1
Sixteen elderly people have died from the flu in Canberra nursing homes in the past three months, a 30% increase on last year's figures. ACT chief health officer Paul Kelly said despite there being a 33% increase in nursing home resident deaths from the flu between 2016 and 2017, due to the overall impact on the community there was not a proportionately significant difference
Extra stocks of flu jab ordered amid fears of winter epidemic
Additional stocks of the seasonal flu vaccine have been ordered by the HSE amid mounting fears of an epidemic this winter. Some 850,000 doses of the vaccine have been purchased - the same number as last year. However, a "contingency" supply of 100,000 doses have also been bought which the Executive "expect to draw down."
General Influenza News
Doctors and health experts are already strongly recommending people get vaccinated against flu
Patients who wish to get vaccinated ought to contact their own GP now. There is no need to worry as health authorities have vaccines in stock. Get vaccinated now in advance of the expected flu outbreak wave which is expected to take off next January
Manitoba launches flu vaccination campaign
In Canada, Manitoba residents are being urged to get vaccinated against the flu for free, as health authorities expect this season to be severe; some people might have access to FluMist instead of a regular flu shot
Corrèze : three things you should know before getting your flu shot from a pharmacist
La Montagne explains why people need to be vaccinated against the flu, where they can get vaccinated and how much it is likely to cost them for a flu shot
Flu jab 2017: Side effects and possible reactions to the winter injection
While it’s important to be vaccinated, the flu shot does come with certain side-effects. According to the NHS, these include a mild fever and slight muscle aches for a couple of days
Worst influenza wave for years feared by local health experts
With colder temperatures this autumn, the risk of becoming infected with the flu virus increases sharply.Last year, the number falling sick with flu in Germany has risen, but, many fear this year could be much worse
Concerns raised about "deadly" flu which could be worst to hit UK in 50 years
Heightened concerns’ have been raised by hospital bosses about a strain of flu which could be deadliest to hit the UK in 50 years. South Warwickshire Foundation Trust (SWFT) chief executive Glen Burley says the UK usually follows the same impact of flu as felt in Australia. And during their winter the number of deaths from the virus was more nearly three times that of the year before, when 27 people died from the illness. This winter more than 72 have died and some 170,000 cases been confirmed. There have also been some reports that the flu jab does not work on the strain of flu, but Mr Burley says this is not the case.
Prepare to fight the Flu!
More than 1.8 million people in Scotland are being urged to get their flu vaccine as early as possible this winter to help protect themselves. People with health conditions which can make them more vulnerable to flu such as heart disease, diabetes are particularly at risk and need to vaccinate themselves
Residents urged to get flu vaccine after targets missed last year
According to Public Health England, last year's flu vaccination programme reduced the risk of flu in children who received the vaccine by 65.8% compared to those that didn't. Research commissioned by AstraZeneca has also highlighted the impact of child ...
Health Officials Say First Flu Case Reported in South Dakota
South Dakota health officials are reporting the first flu case of the season. The Department of Health says the influenza A case involves a Lawrence County resident in his or her 20s. Health officials are encouraging a flu vaccine for everyone over 6 months of age. Last season, nearly 54 percent of South Dakotans got a flu shot, the second highest vaccination rate in the nation.
The Oberallgau health authorities are strongly recommending that people get vaccinated against flu for the coming season now
The 2016-17 seasonal flu outbreak hit the elderly in the region worse than all others and many fear this coming flu season may be even worse. Regional Vaccination groups say both healthcare workers and the elderly need to be protected and current vaccination take-up rates are too low
Experts are warning of severe flu outbreak season
Twice as many flu cases were reported in Australia over the last winter so many Austrian health experts have sounded the alarm about the likelihood of a severe flu season in the coming months and advice flu vaccination for at risk groups
Mums & children missing flu jab in south Wiltshire
Not enough pregnant Mums, or children aged under 4, are coming forward to get their free flu jab in south Wiltshire, UK. Last year, fewer than half of the people in both of those most 'at risk' groups took advantage of having the free jab
Here's why you're about to see actress Judith Light everywhere, talking about flu shots
Yoga practitioner and actress Judith Light is an outspoken advocate of people getting an annual flu vaccination and is working with the National Foundation for Infectious Diseases in the U.S.
Getting an influenza vaccination has never been easier but only half the population will get one
Getting an influenza vaccination has never been easier but only half the population will get one
University of Alabama researcher plots anti-vaccination tweets
An autism researcher at the University of Alabama is helping track social media use by people who publicly advocate against the use of vaccines. Assistant psychology professor Theodore S. Tomeny and colleagues have used a computer algorithm to analyze almost 500,000 tweets over a five-year period that included the words "autism" and "vaccines"
Over 250,000 will fall ill due to flu season, minister warns
Over half the Maltese population, or at least 250,000, will fall ill as influenza season picks up next January, health minister Chris Fearne has warned. Fearne’s stark warning was made in an intervention during parliamentary questions on Budget day, as he prepares to launch the government’s vaccination campaign
Why I won't let doctors give my 8-year-old son Max the flu vaccine at school
Columnist Katie Hopkins explains why she refuses to get her son vaccinated against the flu as he is ‘fit and healthy’; Dr Ellie Cannon answers her by stating why the flu shot is needed for children
NHS bosses say staff have a “professional duty” to have the flu vaccine
NHS England, Public Health England, the Department of Health and NHS Improvement have unveiled measures to boost the uptake of flu vaccination including writing to doctors, nurses and other healthcare workers to remind them of their professional duty to protect patients by being vaccinated
Burden of disease
4,467 Portuguese people died because of the flu and the cold last winter
Last winter, the flu killed more Portuguese people than was expected at this time of year. According to a report by the Ricardo Jorge Institute, the flu and the cold killed 4,467 people in Portugal, a 27% increase in estimated mortality. The vast majority of victims were over 45 and women were slightly more affected than men
12 swine flu deaths in city this year: Delhi government
Swine flu has claimed 12 lives, including eight of Delhi residents, in the Indian national capital this year, Health Minister Satyendar Jain has said. The official data provided by him, however, contradicts the count of fatalities reported from various hospitals in the city
Vital influenza vaccines in short supply
The shortage of influenza vaccine is causing concern among people in the valley. The drug dealers in the valley are facing erratic supply of vaccine which irks the huge rush of people who are in need of this vaccine. Sakeena Zahoor, a resident of Bohri Kadal, said she needed the vaccine for her mother. “I searched everywhere in Lal Chowk, but in vain. My mother has severe flu and dry cough, and her condition further deteriorates in winters. I need the vaccine now,” she said. “Local hospitals do not stock influenza vaccines. People need to buy it from markets.” A Srinagar-based drug distributor said they have been getting limited supply of the vaccine.
Health authorities braced for virulent and twice as widespread flu season
Malta's health authorities are bracing themselves for an influenza season they predict to be more widespread than usual and at least twice as widespread as last year's, according to statistical models the Health Department has been using for the last three years to predict seasonal influenza trends.
Health ministry’s safety tips after H1N1 death in Oman
An Oman resident has died from the H1N1 flu virus, the Ministry of Health has announced. Government health officials have acted to reassure residents that all protocols are in place following the death, and issued guidance on how to avoid the virus