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"Seqirus Media Monitoring" 20th Oct 2017

News Highlights
Credit Suisse: CSL Limited shares are set to outperform Analysts at Credit Suisse have slapped an outperform rating on shares in CSL; Seqirus, CSL’s influenza vaccine division is growing revenue and is on the path to profitability according to management
Roche 9-month Group Sales Rise; Confirms FY17 Forecast - Quick Facts Roche reported that its Group sales for the first nine months of the year increased 5% to 39.43 billion Swiss francs from last year's 37.51 billion francs; there were lower sales of Tarceva, Avastin and Tamiflu
Maryland is developing the next generation of life-saving vaccines Immunomic Therapeutics' Athanasia Anagnostou writes in favour of vaccinations and urges people in her state of Maryland to get vaccinated against the flu and talk to their family doctor to ensure their vaccinations are up to date
New insights into vaccination debate Governments wielding a 'big stick' for compliance is unlikely to solve the problem of making parents vaccinate their children. Flinders University and research colleagues are investigating a less polarising approach to the issue of childhood vaccination refusal or hesitancy. The findings are described in the paper "Understanding the perceived logic of care by vaccine-hesitant and vaccine-refusing parents: A qualitative study in Australia" published in PLOS ONE
Newly discovered viral marker could help predict flu severity in infected patients Flu viruses contain defective genetic material that may activate the immune system in infected patients, and new research published in PLOS Pathogens suggests that lower levels of these molecules could increase flu severity
Flu simulations suggest pandemics more likely in spring, early summer New statistical simulations suggest that Northern Hemisphere flu pandemics are most likely to emerge in late spring or early summer at the tail end of the normal flu season, according to a new study
Maryland and Georgia Researchers Find Racial Differences in Trust Determine Adult Vaccine Uptake There is a consistent racial disparity in seasonal influenza vaccination, with African American adults receiving the vaccine at lower rates than whites. Overall, flu vaccination rates for adults fall below target. Because African Americans experience a greater burden of chronic diseases that increases their risk of serious complications from the flu, there is a distinct impetus to raise vaccination rates within this group
New H7N9 bird flu strain in China has pandemic potential: study Lab experiments on a new strain of the H7N9 bird flu circulating in China suggest the virus can transmit easily among animals and can cause lethal disease, raising alarms that the virus has the potential for triggering a global human pandemic, researchers reported on Thursday
Green Cross starts to develop high-dose flu vaccine for seniors In South Korea, Green Cross said that it has received approval from the Ministry of Food and Drug Safety to begin domestic phase 1 clinical trials for GC3114, a high-dose quadrivalent influenza vaccine for the elderly
Seqirus mentions
Credit Suisse: CSL Limited shares are set to outperform
Analysts at Credit Suisse have slapped an outperform rating on shares in CSL; Seqirus, CSL’s influenza vaccine division is growing revenue and is on the path to profitability according to management
Flu shots for seniors
There are two different flu shots – Fluzone High Dose and FLUAD – that are designed specifically for people age 65 and older; FLUAD contains adjuvant MF59 that also helps create a stronger immune response. In a 2012 Canadian observational study, FLUAD was 63 percent more effective than a regular flu shot
Is the CSL Limited CEO paid too much?
CSL shareholders were keen to resolve an ongoing dispute about executive pay at the company’s AGM but some weren’t happy after the CEO enjoyed another pay increase despite remuneration concerns raised last year. David Anstice, Chairman of CSL’s Human Resources and Remuneration Committee, said Mr Perreault and his team delivered above target earnings growth, sector leading growth in plasma collection volumes, launched new products, ensured the Seqirus strategic plan remains on track, and secured an entry strategy into China
Pandemic Influenza News
Will the World's Most Worrying Flu Virus Go Pandemic?
The CDC keeps a Most Wanted list for flu viruses and evaluates every potentially dangerous strain, with two scores out of 10—one reflecting how likely they are to trigger a pandemic, and another that measures how bad that pandemic would be. At the top of the list, with scores of 6.5 for emergence and 7.5 for impact, is H7N9
The next wave of bird flu could be worse than ever
Researchers isolated the H7N9 virus from a fatal human case and tested it and two genetically modified versions in ferrets, which are susceptible to both human and bird flu viruses. The tested viruses can spread to other ferrets through airborne fluid droplets like those released by a cough or a sneeze, sometimes turning deadly, researchers report October 19 in Cell Host and Microbe.
Dutch bird flu outbreak leads to trade bans
Hong Kong has banned regional Dutch poultry products following an outbreak of low pathogenic avian influenza which led to the culling of more than 40,000 birds
New H7N9 bird flu strain in China has pandemic potential: study
Lab experiments on a new strain of the H7N9 bird flu circulating in China suggest the virus can transmit easily among animals and can cause lethal disease, raising alarms that the virus has the potential for triggering a global human pandemic, researchers reported on Thursday
Dept of Disease Control moves to prevent bird flu outbreak
In Thailand, the Department of Disease Control is implementing measures to prevent the spread of avian flu during the end of the rainy season, following outbreaks in many other countries
Industry News
Roche 9-month Group Sales Rise; Confirms FY17 Forecast - Quick Facts
Roche reported that its Group sales for the first nine months of the year increased 5% to 39.43 billion Swiss francs from last year's 37.51 billion francs; there were lower sales of Tarceva, Avastin and Tamiflu
Maryland is developing the next generation of life-saving vaccines
Immunomic Therapeutics' Athanasia Anagnostou writes in favour of vaccinations and urges people in her state of Maryland to get vaccinated against the flu and talk to their family doctor to ensure their vaccinations are up to date
3 Reasons Cara Therapeutics Is a Better Growth Stock Than Novavax
Novavax announced very promising results from preclinical testing of its NanoFlu influenza vaccine in August. The vaccine could turn out to be a big winner for the company, but it's still early. Novavax began a phase 1/2 study in September. There are quite a few hurdles to jump before the company can claim success with NanoFlu.
Academic studies
New insights into vaccination debate
Governments wielding a 'big stick' for compliance is unlikely to solve the problem of making parents vaccinate their children. Flinders University and research colleagues are investigating a less polarising approach to the issue of childhood vaccination refusal or hesitancy. The findings are described in the paper "Understanding the perceived logic of care by vaccine-hesitant and vaccine-refusing parents: A qualitative study in Australia" published in PLOS ONE
Newly discovered viral marker could help predict flu severity in infected patients
Flu viruses contain defective genetic material that may activate the immune system in infected patients, and new research published in PLOS Pathogens suggests that lower levels of these molecules could increase flu severity
Flu simulations suggest pandemics more likely in spring, early summer
New statistical simulations suggest that Northern Hemisphere flu pandemics are most likely to emerge in late spring or early summer at the tail end of the normal flu season, according to a new study
Maryland and Georgia Researchers Find Racial Differences in Trust Determine Adult Vaccine Uptake
There is a consistent racial disparity in seasonal influenza vaccination, with African American adults receiving the vaccine at lower rates than whites. Overall, flu vaccination rates for adults fall below target. Because African Americans experience a greater burden of chronic diseases that increases their risk of serious complications from the flu, there is a distinct impetus to raise vaccination rates within this group
Pediatric influenza news
Free flu vaccines for Queensland pre-schoolers
Queensland kids under five will get free flu vaccines from next year and the government will provide funds to enable a faster flu diagnosis to ease the burden on the state's hospitals. Health experts, including representatives from the WHO, gathered in Brisbane to develop further strategies to combat the flu
Brad Hazzard lobbies federal govt for free flu jabs for all kids in NSW
In Australia, Health Minister Brad Hazzard is lobbying the federal Government to provide free influenza vaccines for young children. Under the plan vaccinations would be free for children from six months to five years and administered at GPs and schools every year
Over 65’s influenza news
Green Cross starts to develop high-dose flu vaccine for seniors
In South Korea, Green Cross said that it has received approval from the Ministry of Food and Drug Safety to begin domestic phase 1 clinical trials for GC3114, a high-dose quadrivalent influenza vaccine for the elderly
Myths and Facts about the prospect of flu vaccination
The article discusses facts and myths surrounding topics such as: who should be vaccinated and why, whether healthy elderly people should get vaccinated and how it helps them
Flu Vaccination for the elderly
People aged 60 and over should be vaccinated against influenza. There are several vaccines available: a standard vaccine with antigens against three viral strains, and a vaccine with antigens against four strains.
Vaccination of adults and elderly is at unsatisfactory level, says Brazilian immunization group
The levels of vaccination among the elderly seem to be low, although the precise numbers are uncertain. Many diseases, particularly among the elderly, resulting from complications linked to the flu could easily be avoided if the immunization levels were much higher
Flu vaccine helps avoid hospitalisation of older people
A study by the University of Barcelona showed that people over 65 who have received the flu vaccine are less likely to require hospitalisation because of the virus, particularly if they do not have other medical conditions and are between 65 and 79 years old
MD of Barmer Berlin flags up low vaccination rate against the flu among seniors as a significant health risk
The past flu season of 2016/2017 in Berlin led to 900 flu-related deaths. The influenza wave was particularly severe for people over 65 years of age. "In elderly people, influenza viruses can lead to complicated disease progression. The vaccination rate is only 35%. Anyone who wants to protect themselves from influenza should be vaccinated now, "says Gabriela Leyh, Managing Director of BARMER Berlin
Protect your heart health by getting vaccinated
While getting vaccinated is important for people of all ages, it’s especially important for adults with heart disease. They are more likely to have serious complications from common diseases such as influenza or pneumonia that vaccination can help prevent
General Influenza News
Flu vaccination across South Tyrol
The flu is a serious health hazard due to its spread, contagion, and possible serious complications, that can lead to death. Health authorities are keen to get as many people as possible vaccinated, particularly the elderly and at risk groups
Unprotected hospital staff: local Basle canton hospital employees are not getting flu vaccinations putting many at risk
Experts fear a severe flu wave in Europe. Hospital staff across the Basel Canton cannot be left out of vaccinations. In the Baselland canton, only 20 percent of healthcare employees follow the vaccination rules recommended by the federal government
Influenza 2017-2018: why you need to vaccinate and how effective it will be, InfluNet now in action
The Italian Ministry of Health has launched its InfluNet network, which aims to collect data and all reports relating to influenza symptoms and flu-like syndromes, as well as the number of influenza sick people
Influenza Vaccine 2017: Cost, Composition, Contraindications and Side Effects
Influenza vaccine is the only weapon to defeat the virus and it is strongly recommended, particularly for at risk groups. The benefits are remarkable, however some side effects and some contraindications exist
PACA: flu vaccine for 2018 has arrived
In the south-east region of France, the flu vaccine for 2018 is now available. This is an area which is below the national average for flu shot uptake, particularly among the 65-69 years old group
The influenza vaccination campaign in Zacatlan has started
Local Mexican health authorities said they will begin a campaign of vaccination against the flu from next Monday, focusing on those most at risk.
SESA will provide more than 232,000 doses of influenza vaccines
As part of the upcoming winter season, the Ministry of Health (Sesa) in Tlaxcala, Mexico, will have more than 232,000 doses of influenza vaccines, which it will provide for groups at risk. This vaccine dose provides protection against the viruses AH1N1, AH3N2 and Influenza type B.
Northamptonshire people urged to take up flu vaccine offer
People in Northamptonshire, UK, who are the most vulnerable to flu are being urged to protect themselves and their family this winter by having a vaccination
Paula Radcliffe urges at-risk groups to have flu vaccine
Following warnings from NHS England that the UK could face a significant increase in flu cases this winter after a heavy flu season in Australia and New Zealand, it is important that people, particularly those in clinical at-risk groups, think about protecting themselves against the virus this season. Just over half (51.4%) of those in at risk groups did not get vaccinated against the flu virus in 2016/2017, although vaccination is offered to them free of charge as part of the national immunisation programme.
Threat of potent flu virus spurs urgency of vaccination, say Calgary health officials
Alberta Health has procured enough vaccine to cover 35% of the population, said a local health expert, though Albertans overly reluctant to receive a shot don't seem likely to exhaust the supply. "Last year we had 27 per cent vaccinated and we'd certainly like to see more, especially if there's vaccine to cover 35 per cent," they said
Typical flu season expected for northern Nova Scotia
The upcoming flu season shouldn’t be any busier than previous years, but northern Nova Scotia’s chief medical officer of health is warning against complacency. Dr. Ryan Sommers is urging people to get a free flu shot this year, especially those in high risk categories, first responders and health care workers
Flu Vaccine Fake News That Goes Viral During The Flu Season
Winter is almost here, which means flu season is just around the corner. It also means that anti-flu vaccine misinformation will go viral again. There are many common myths regarding the flu shot as well as posts being shared on Facebook spreading misinformation which are examined in this article
What Australia"s record-breaking flu season means for Singapore
Australia's severe outbreak of flu may appear to be tapering off in some places, but Singaporeans are still encouraged to get vaccinated before travelling there, said the Ministry of Health
A quarter of French people against vaccinations
A record number of French people are sceptical with regard to vaccines, a reaction partly due to recent controversies on hepatitis B vaccine and the seasonal flu shot. The government launched an information website "Vaccination Info Service" 6 months ago which has been visited by almost a million people
Bad fridge at San Diego VA means up to 1,500 got ineffective flu shots
A refrigerator on the blink at the San Diego VA hospital in La Jolla has resulted in up to 1,540 veterans and employees receiving flu shots that are now considered potentially ineffective. A CDC guideline for handling vaccines says errors like this, which require repeat doses, can result in a loss of patient confidence
Mexico City health authorities have 2,737,000 doses of influenza vaccine to get people protected
Health Secretary, Armando Ahued Ortega, launched a Vaccination Campaign against the seasonal influenza for the 2017-2018 season, which the objective of protecting those groups which are most vulnerable to the flu virus
Egg Allergies and the flu vaccine: What do I need to know?
A recent study conducted by the CDC found that the incidence of severe reaction to the flu vaccine among egg-allergic and non-allergic children was literally one in a million. Given those findings, the recommendations have been revised so that children with an egg allergy can be safely vaccinated in any inpatient or outpatient setting where the provider feels comfortable recognizing and managing allergic reactions
Health staff offered prizes for flu jabs
In Northern Ireland, health trusts are running prize raffles to encourage staff to get the winter flu jab. Uptake among front-line staff is so low, the health trusts are missing targets; last year, the uptake was only 29%. All staff working within the trusts are entitled to the influenza vaccine free of charge
Govt will cough up $600k for new flu testing
In Australia, new flu detection technology will generate a better response to the virus, a Mackay doctor says. Mackay Hospital will be one of 15 in Queensland to get "rapid point-of-care testing,” the state government said
What will the 2018 flu vaccine include?
In Australia, while this year’s flu season is only just slowing down after surpassing 200,000 confirmed cases this month, the Australian Influenza Vaccine Committee recently met with the TGA to discuss which viruses should be used in the composition of next year’s influenza vaccines
Southern Health Trust accused of bribing staff to take flu vaccine
In Ireland, disbelief has been expressed at the local Southern Health Trust for organising a raffle for extra annual leave if staff get vaccinated for flu. The Trust has organised an incentive of two free days off if they register to take up the flu vaccine
Burden of disease
Confirmed flu notifications surpass 200,000
As of 16 October there have been a total of 212,365 laboratory confirmed notifications of influenza in Australia this year, according to statistics from the Immunisation Coalition and the Department of Health. Despite the high numbers, the Immunisation Coalition says the true number could be far greater
No dip in swine flu cases in Hyderabad
Despite huge fluctuations in the temperature, swine flu cases continue to register in government and private hospitals in the city of Hyderabad in India
Around 100,000 more cases of respiratory infections in 2017
In Mexico's Quintana Roo, there has been a sharp increase in respiratory infections in 2017; the flu also appears twice a year and around 1.5% of the people who catch the flu also suffer from complications
Oklahoma Health Department: 6 hospitalized from flu this week
The Oklahoma State Department of Health is reporting six new cases of the flu that required hospitalization. The latest admissions to hospitals across Oklahoma bring the season total 26 since Sept. 1. So far, there have been no flu-related deaths in the state
First Flu-Related Death Reported in California for Person Under Age 65: CDPH
Flu season is spreading quickly through San Diego this year with 258 reported cases. That's compared to only 82 flu cases at this time last year. The first flu-related death of the season for a person under age 65 in California was confirmed Thursday, according to the California Department of Public Health
Flu cases show up early in SoCal
Flu season usually peaks much later in California, but already health care providers say quite a few people are testing positive for the virus. Jeanette Sirkin, a nurse practitioner with the Minute Clinic at CVS in Burbank advises people to get in and get their flu shots
Maryland health department reports first flu cases of the season
Maryland’s first seasonal flu cases have been confirmed in three adults in the Baltimore area, the Maryland Department of Health said. One of the people stricken was hospitalized and released. The health department did not release other details about the people who were diagnosed